Lupus Vasculitis: An Overview: Influence Statistics

Expert Impact

Concepts for which they have has direct influence: Systemic lupus erythematosus , Systemic lupus , Lupus erythematosus , Erythematosus sle .

Key People For Systemic Lupus Erythematosus

Top KOLs in the world
#1
David Alan Isenberg
systemic lupus erythematosus patients sle rheumatoid arthritis
#2
Michelle A Petri
systemic lupus erythematosus lupus nephritis patients sle
#3
D Gladman Gladman
psoriatic arthritis systemic lupus erythematosus patients psa
#4
Murray B Urowitz
systemic lupus erythematosus patients sle lupus nephritis
#5
James F Fries
rheumatoid arthritis physical function systemic lupus erythematosus
#6
Norman Talal
sex hormones lupus erythematosus sjögrens syndrome

Lupus Vasculitis: An Overview

Abstract

. Lupus vasculitis (LV) is one of the secondary vasculitides occurring in the setting of systemic lupus erythematosus (SLE) in approximately 50% of patients. It is most commonly associated with small vessels, but medium-sized vessels can also be affected, whereas large vessel involvement is very rare. LV may involve different organ systems and present in a wide variety of clinical manifestations according to the size and site of the vessels involved. LV usually portends a poor prognosis, and a prompt diagnosis is fundamental for a good outcome. The spectrum of involvement ranges from a relatively mild disease affecting small vessels or a single organ to a multiorgan system disease with life-threatening manifestations, such as mesenteric vasculitis, pulmonary hemorrhage, or mononeuritis multiplex. Treatment depends upon the organs involved and the severity of the vasculitis process. In this review, we provide an overview of the different forms of LV, describing their clinical impact and focusing on the available treatment strategies.