 | Qichen ChenDepartment of Hepatobiliary Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union ... |
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Qichen Chen:Expert Impact
Concepts for whichQichen Chenhas direct influence:Early recurrence,Simultaneous resection,Neoadjuvant chemotherapy,Colorectal liver metastases,Colorectal liver,Nac cycles,Optimal timing,Seer database.
Qichen Chen:KOL impact
Concepts related to the work of other authors for whichfor which Qichen Chen has influence:Early recurrence,Endometrial cancer,Neoadjuvant chemotherapy,Colorectal liver metastases,Upfront surgery,Intrahepatic cholangiocarcinoma,Simultaneous resection.
KOL Resume for Qichen Chen
| Year | |
|---|---|
| 2022 | Department of Hepatobiliary Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China. Key Laboratory of Gene Editing Screening and R&D of Digestive System Tumor Drugs, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021, Beijing, China |
| 2021 | Department of Hepatobiliary Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021, Beijing, China. |
| 2020 | Department of Hepatobiliary Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China. |
| 2019 | Department of Hepatobiliary Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021, Beijing, China |
| 2018 | Department of Hepatobiliary Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, PR China. |
| Concept | World rank |
|---|---|
| css iptw | #2 |
| removed nodes patients | #2 |
| nrn ≥13 | #2 |
| bronchopulmonary carcinoids pcs | #2 |
| p0001 nrn | #2 |
| plnr ≥13 worse | #2 |
| ≥13 worse | #2 |
| plnr removed | #2 |
| iptw plnr | #2 |
| values plnr | #2 |
| plnr nrn | #2 |
| worse kaplan | #2 |
| adjustment nrn | #2 |
| worse worse css | #2 |
| worse kaplan meier | #2 |
| plnr ≥13 | #2 |
| analysis iptw adjustment | #2 |
| crlm patients nac | #4 |
| 0359 0950 | #4 |
| level 0584 | #4 |
| dehydrogenase nac | #4 |
| 95 clinical covariates | #4 |
| preoperative ldh levels | #4 |
| 0950 p0030 | #4 |
| p0017 grade | #4 |
| prenac ldh | #4 |
| p0030 grade | #4 |
| psm1 performed | #5 |
| 144 crlm patients | #5 |
| ward validation cohort | #5 |
| recurrence dca | #5 |
| nac hepatectomy | #5 |
| patients crs score | #5 |
| early recurrence dca | #5 |
| crs psm1 | #5 |
| shortterm outcomes psm2 | #5 |
| 40 crlm patients | #5 |
| matching psm2 | #5 |
| psm2 shortterm outcomes | #5 |
| auroc primary cohort | #5 |
| matching psm1 | #5 |
| elderly crlm | #5 |
| nomogram preoperative creatinine | #5 |
| elderly crlm patients | #5 |
| p0017 pfs | #6 |
| preoperative testing markers | #6 |
| nrn css | #6 |
| nac ldh | #7 |
| recurrence constructed | #7 |
| revealed desirable | #7 |
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Prominent publications by Qichen Chen
BackgroundNeutropenia, the major adverse event in chemotherapy, is associated with favourable clinical outcome in several solid tumours. We aimed to investigate the predictive value of neo-adjuvant chemotherapy (NAC)–induced neutropenia for the pathological response and prognosis in colorectal liver metastases (CRLM) patients.MethodsA retrospective review was performed in 141 CRLM patients receiving NAC followed by liver resection. A logistic regression was applied to analyse potential ...
| Known for Patients Neutropenia | Colorectal Liver | Adjuvant Chemotherapy | Multivariate Analysis | Pathological Response |
OBJECTIVES: To investigate the predictive value of the pre-operative D-dimer and gamma-glutamyltranspeptidase (GGT) for the prognosis in colorectal liver metastases (CRLM) patients after hepatic resection.
METHODS: Two hundred and ninety-two patients between December 2008 and December 2016 and 101 patients at our center from January 2017 to December 2018 were selected as a training set and validation set, respectively. The combination of the pre-operative D-dimer and GGT status (CPDG ...
| Known for Colorectal Liver Metastases | Crlm Patients | Hepatic Resection | Dimer Levels | Complications Survival |
BACKGROUND: This study aimed to investigate the predictive significance of preoperative red cell volume distribution width (RDW) level for prognosis and to establish nomograms incorporating preoperative blood markers to predict postoperative complications and survival in patients with colorectal liver metastases (CRLM).
METHODS: This retrospective study included 380 enrolled CRLM patients who underwent hepatic resection. Predictors of postoperative complications were explored using ...
| Known for Colorectal Liver Metastases | Crlm Patients | Optimal Cutoff Point | Incorporating Preoperative | Postoperative Complications |
Background: To investigate the predictive role of D-dimer and its combination of preoperative CA19-9 for lymph node metastasis (LNM) and prognosis in intrahepatic cholangiocarcinoma (ICC) patients who underwent curative-intent resection.
Methods: One hundred and seventy-three patients admitted to our hospital between April 2012 and December 2018 were included. The combination of preoperative D-dimer and CA19-9 (CPDC) was scored as 0 (decreased D-dimer levels with decreased CA19-9 ...
| Known for Curative Resection | Icc Patients | Lymph Node | Intrahepatic Cholangiocarcinoma | Ca19 9 |
BACKGROUND: To establish upgraded nomograms incorporating neoadjuvant chemotherapy (NAC)-related factors and preoperative testing markers to predict postoperative complications, progression-free survival (PFS) and overall survival (OS) in patients with colorectal liver metastases (CRLM).
METHODS: Multivariate regression analyses were used to reveal independent predictors for postoperative complications, PFS and OS. Nomograms incorporating independent predictors were constructed, and ...
| Known for Colorectal Liver Metastases | Neoadjuvant Chemotherapy | Crlm Patients | Independent Predictors | Nac Cycles |
Lymphadenectomy is associated with poor survival in patients with gastrointestinal stromal tumors.
[ PUBLICATION ]
Background: Current clinical practice suggests lymphadenectomy for gastrointestinal stromal tumor (GIST) patients with enlarged lymph nodes, but little is known about the influence of lymphadenectomy on long-term survival.
Methods: This population-based study consisted of 3,819 non-metastatic GIST patients diagnosed between January 1st, 2001, to December 31st, 2015, from the Surveillance, Epidemiology, and End Results (SEER) database. Kaplan-Meier methods and Cox proportion regression ...
| Known for Gastrointestinal Stromal Tumors | Gist Patients | Seer Database | Tumor Size | Survival Css |
Chinese expert recommendations on management of hepatocellular carcinoma during COVID-19 pandemic: a nationwide multicenter survey
[ PUBLICATION ]
BACKGROUND: This study aimed to investigate the work status of clinicians in China and their management strategy alteration for patients with hepatocellular carcinoma (HCC) during the COVID-19 pandemic.
METHODS: A nationwide online questionnaire survey was conducted in 42 class-A tertiary hospitals across China. Experienced clinicians of HCC-related specialties responded with their work status and management suggestions for HCC patients during the pandemic.
RESULTS: 716 doctors responded ...
| Known for Hepatocellular Carcinoma | Patients Pandemic |
ObjectiveTo investigate the differences in the efficacy of hepatic resection combined with tyrosine kinase inhibitor (TKI) therapy versus TKI therapy alone and the timing of the TKI therapy and hepatic resection for resectable liver metastases from gastrointestinal stromal tumours (GISTs).MethodsThis was a retrospective review of 43 patients confirmed to have resectable liver metastases from GISTs who received TKI treatment alone or the therapy model of hepatic resection combined with ...
| Known for Multivariate Analysis | 95 Patients | Survival Pfs |
Prognostic nomogram for predicting long-term survival in bronchopulmonary carcinoid tumor patients receiving resection
[ PUBLICATION ]
Background: We analyzed bronchopulmonary carcinoid tumor (BPC) patients receiving resection from the Surveillance, Epidemiology, and End Results (SEER) database to identify the predictive factors of their survival. Then, we developed and validated nomograms to predict overall survival (OS) and cancer-specific survival (CSS) in BPC patients.
Methods: BPC patients registered in the SEER database were included. They were divided into a training set and an internal validation set (7:3). BPC ...
| Known for Tumor Size | External Validation | Seer Database | Calibration Plots | Factors Identified |
OBJECTIVE: The aim of the present study was to compare outcomes after curative intent radiofrequency ablation and resection in patients with resectable liver metastases of Gastrointestinal Stromal Tumours (GISTs) after pre-operative tyrosine kinase inhibitor (TKI) treatment.
METHODS: We retrospectively analysed data from 25 patients diagnosed with resectable liver metastases from GISTs who received pre-operative TKI treatment, who received radiofrequency ablation or resection and ...
| Known for Liver Metastases | Hepatic Resection | Postoperative Complications | Prognostic Factor |
BACKGROUND: It is necessary to identify valuable predictors of primary lymph node metastasis and prognosis for patients with synchronous colorectal cancer liver metastases (CRLM) with simultaneous resection of colorectal cancer (CRC) and liver metastases. This study constructed nomograms especially incorporating preoperative testing markers to predict primary lymph node metastases and prognosis in CRLM patients.
METHODS: By the highest Youden index (sensitivity + 1-specificity), the ...
| Known for Metastasis Based | Multivariate Analysis | Dehydrogenase Ldh |
What is the optimal number of neoadjuvant chemotherapy cycles for resectable colorectal liver oligometastases?
[ PUBLICATION ]
Background: The optimal number of neoadjuvant chemotherapy (NAC) cycles for resectable colorectal liver oligometastases (CLOM) remains unclear. The aim of this study was to investigate the optimal number of NAC cycles.
Methods: One hundred twenty-nine consecutive patients were included in this study. X-tile analysis was implemented to investigate the optimal cut-off point for NAC cycles. Propensity score matching was performed to reduce selection bias. Kaplan-Meier curves and Cox risk ...
| Known for Colorectal Liver |
