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    • Simon Horenblas: Influence Statistics

      Simon Horenblas

      Simon Horenblas

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      Department of Urology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands | Netherlands Cancer Institute, Amsterdam, Netherlands; | ...

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      Simon Horenblas:Expert Impact

      Concepts for whichSimon Horenblashas direct influence:Penile cancer,Penile carcinoma,Sentinel node,Node biopsy,Lymph node,Bladder cancer,Prostate cancer,Cell carcinoma.

      Simon Horenblas:KOL impact

      Concepts related to the work of other authors for whichfor which Simon Horenblas has influence:Penile cancer,Radical cystectomy,Lymph node,Cell carcinoma,Neoadjuvant chemotherapy,Human papillomavirus,Urinary bladder.

      KOL Resume for Simon Horenblas

      Year
      2022

      Department of Urology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands

      2021

      Urology Department, The Netherlands Cancer Institute – Antoni van Leeuwenhoek [NCI-AVL] Hospital, Amsterdam, The Netherlands

      2020

      Department of Urology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.

      2019

      Department of Radiation Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands

      2018

      Division of Surgical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands

      2017

      Department of Urology, The Netherlands Cancer Institute—Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands

      2016

      Department of Urology, The Netherlands Cancer Institute – Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands

      2015

      Netherlands Cancer Institute‐Antoni van Leeuwenhoek Hospital Department of Urology Amsterdam the Netherlands

      2014

      Department of Urology, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, Netherlands

      2013

      Urologic Oncology and Department of Urology, The Netherlands Cancer Institute, Amsterdam, The Netherlands

      2012

      The Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Departments of Urology and Radiation Oncology, Amsterdam

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      Sample of concepts for which Simon Horenblas is among the top experts in the world.
      Concept World rank
      pplns patients #1
      tomography sentinel #1
      penis sccp #1
      groins patients #1
      studer type neobladder #1
      penile preservation #1
      spect portable γ #1
      primary penile carcinoma #1
      pndisease #1
      63 pt3n0 #1
      sartorius muscle transposition #1
      cn0 patients #1
      penile cancer stage #1
      patients mibc mbc #1
      g2t1 penile cancer #1
      nonpalpable recurrence 80 #1
      median lnc #1
      invasive staging groins #1
      pet mortality #1
      107 inguinal regions #1
      gc neoadjuvant setting #1
      peca node biopsy #1
      institute colon shuffle #1
      nodes improved #1
      brachytherapy cystectomy #1
      conventional pde head #1
      pelvis penile #1
      868962 #1
      ureteric occlusion #1
      sccp csm #1
      patients penile carcinoma #1
      g2t1 disease #1
      patients pn3 disease #1
      radical ilnd #1
      irregular nodal border #1
      nac nar #1
      analysis bilateral plnd #1
      adversities treatment #1
      extravesical lesions malignancy #1
      invasion tunica albuginea #1
      penile carcinoma #1
      30 detection rates #1
      treatment regional #1
      bengmark protocol #1
      pelvic nodal involvement #1
      carboplatin data #1
      lnc pndisease #1
      p0001 centralization #1
      occult metastasis pet #1
      urinary diversions cystectomy #1
      Sign-in to see all concepts, it's free!

      Prominent publications by Simon Horenblas

      KOL-Index: 18314

      Laparoscopic evaluation of sentinel nodes is useful for staging prostate cancer, but preoperative localization of deep abdominal sentinel nodes with planar lymphoscintigraphy is difficult. We evaluated the value of SPECT/CT for detecting and localizing sentinel nodes in prostate cancer.

      METHODS: (99m)Tc-nanocolloid was injected peri- and intratumorally, guided by transrectal ultrasonography, in 46 patients with prostate cancer of intermediate prognosis. Patients underwent planar imaging ...

      Known for Sentinel Nodes | Planar Imaging | Spect Patients | Prostate Carcinoma | Lymph Node
      KOL-Index: 15527

      BACKGROUND: Knowledge regarding the lymphatic drainage pattern of penile cancer is the basis for the extent of inguinal lymph node dissection for this disease.

      OBJECTIVE: To prospectively analyze the lymphatic drainage pattern of penile carcinoma using SPECT-CT and evaluate the implications for the extent of inguinal lymph node dissection.

      DESIGN, SETTING, AND PARTICIPANTS: The lymphatic drainage patterns of 50 patients scheduled for dynamic sentinel node biopsy were analyzed using a ...

      Known for Lymphatic Drainage | Lymph Node | Penile Carcinoma | Anatomical Mapping | Pelvic Region
      KOL-Index: 15297

      The purpose of this study was to compare the lymphoscintigraphic drainage patterns of a hybrid sentinel node tracer consisting of the fluorescent dye indocyanine green (ICG) and (99m)Tc-nanocolloid with the drainage pattern of (99m)Tc-nanocolloid alone, the current standard tracer in many European countries.

      METHODS: Twenty-five patients with a melanoma in the head and neck region (n = 10), a melanoma on the trunk (n = 6), or penile carcinoma (n = 9) who were scheduled for sentinel node ...

      Known for Sentinel Node | Tracer Indocyanine | 99mtc Nanocolloid | Hybrid Fluorescent | Lymphoscintigraphy Spect
      KOL-Index: 14655

      We analyzed the management of regional lymph nodes in 110 patients with squamous cell carcinoma of the penis treated at the Netherlands Cancer Institute between 1956 and 1989 with curative intent. Of 66 patients who presented with unsuspected nodes 57 were placed on a surveillance program, while lymph node dissection was performed in 5 (with adjuvant external radiation therapy in 1) and 4 were treated with external radiation therapy only. The management of 40 patients with clinically ...

      Known for Lymph Node | Squamous Cell Carcinoma | Regional Recurrence | Adjuvant Radiotherapy | Aged Neoplasm
      KOL-Index: 14637

      BACKGROUND: Sentinel node (SN) biopsy in penile cancer is typically performed using a combination of radiocolloid and blue dye. Recently, the hybrid radioactive and fluorescent tracer indocyanine green (ICG)-(99m)Tc-nanocolloid was developed to combine the beneficial properties of both radio-guidance and fluorescence imaging.

      OBJECTIVE: To explore the added value of SN biopsy using ICG-(99m)Tc-nanocolloid in patients with penile carcinoma.

      DESIGN, SETTING, AND PARTICIPANTS: Sixty-five ...

      Known for Blue Dye | Sentinel Node | Fluorescent Tracer | Penile Carcinoma | Fluorescence Imaging
      KOL-Index: 14277

      PURPOSE: Sentinel node biopsy is used to evaluate the nodal status of patients with clinically node-negative penile carcinoma. Its use is not widespread, and the majority of patients with clinically node-negative disease undergo an elective inguinal lymph node dissection. Reservations about the use of sentinel node biopsy include the fact that most current results come from one institution and the supposedly long learning curve associated with the procedure. The purpose of this study was ...

      Known for Node Biopsy | Squamous Cell | Penile Carcinoma | Negative Sentinel | Nodal Status
      KOL-Index: 13750

      BACKGROUND: The efficacy of neoadjuvant chemotherapy (NAC) for muscle-invasive bladder cancer (BCa) was established primarily with methotrexate, vinblastine, doxorubicin, and cisplatin (MVAC), with complete response rates (pT0) as high as 38%. However, because of the comparable efficacy with better tolerability of gemcitabine and cisplatin (GC) in patients with metastatic disease, GC has become the most commonly used regimen in the neoadjuvant setting.

      OBJECTIVE: We aimed to assess ...

      Known for Neoadjuvant Chemotherapy | Mvac Gc | Invasive Bladder | Response Rates | Nac Regimens
      KOL-Index: 13448

      BACKGROUND: The European Association of Urology (EAU) guidelines advise an elective bilateral lymphadenectomy in clinically node-negative (cN0) patients with high-risk penile carcinoma (≥pT2, G3, or lymphovascular invasion [LVI]).

      OBJECTIVE: Our aim was to assess prognostic factors for occult metastasis and to determine whether current EAU guidelines accurately stratify patients at high risk.

      DESIGN, SETTING, AND PARTICIPANTS: Data of 342 cN0 patients with histologically proven invasive ...

      Known for Lymph Node | Negative Patients | Occult Inguinal | Penile Carcinoma | Eau Guidelines
      KOL-Index: 13398

      BACKGROUND: The role of cytoreductive nephrectomy in metastatic clear cell renal cell carcinoma (ccRCC) is controversial.

      OBJECTIVE: To determine the outcome of patients with metastatic ccRCC who receive sunitinib prior to planned nephrectomy.

      DESIGN, SETTING, AND PARTICIPANTS: The study combined the data from two prospective phase 2 studies that assessed upfront sunitinib (12-16 wk) prior to nephrectomy in previously untreated patients with metastatic renal cell carcinoma (RCC). ...

      Known for Planned Nephrectomy | Cell Renal | Sunitinib Prior | Metastatic Clear | Treatment Break
      KOL-Index: 13005

      PURPOSE: To determine whether the apoptotic index, the Ki67 index, and the expression of the p53, cyclin D1, and retinoblastoma genes correlate with local control, overall survival, and time to distant metastases in invasive bladder cancer treated with external beam radiation.

      METHODS AND MATERIALS: Paraffin-embedded pretreatment biopsies from 83 patients with invasive transitional cell carcinoma of the bladder were scored morphologically for apoptosis and immunohistochemically for Ki67, ...

      Known for Cyclin D1 | Radiation Response | Transitional Cell | Local Control | Retinoblastoma Gene
      KOL-Index: 12844

      PURPOSE: We determine the value of dynamic sentinel node biopsy for staging squamous cell carcinoma of the penis.

      MATERIALS AND METHODS: A total of 90 patients with clinically node negative penile cancer were prospectively entered in this study. Preoperative lymphoscintigraphy was performed after intradermal injection of 99mtechnetium nanocolloid around the primary tumor. The sentinel node was intraoperatively identified with the aid of intradermal administered patent blue dye and a ...

      Known for Sentinel Node | Penile Cancer | Preoperative Lymphoscintigraphy | 88 Patients | Primary Tumor
      KOL-Index: 12832

      PURPOSE: To compare radiotherapy and chemotherapy effects on long-term risks of second malignant neoplasms (SMNs) and cardiovascular diseases (CVDs) in testicular cancer (TC) survivors.

      PATIENTS AND METHODS: In our nationwide cohort comprising 2,707 5-year TC survivors, incidences of SMNs and CVDs were compared with general-population rates by calculating standardized incidence ratios (SIRs) and absolute excess risks (AERs). Treatment effects on risks of SMN and CVD were quantified in ...

      Known for Testicular Cancer | Smns Cvd | Cardiovascular Disease | Chemotherapy Risk | Radiationinduced Neoplasms
      KOL-Index: 12783

      PURPOSE: Sentinel lymph node biopsy is emerging as a promising method for inguinal lymph node staging of penile squamous cell carcinoma. In the current systematic review we evaluated the accuracy of sentinel lymph node biopsy for inguinal lymph node staging of penile squamous cell carcinoma and studied possible influential factors.

      MATERIALS AND METHODS: MEDLINE®, Scopus®, ISI®, Ovid SP®, Springer, ScienceDirect® and Google™ Scholar were searched by the key words "(penile OR penis) AND ...

      Known for Node Biopsy | Sentinel Lymph | Squamous Cell | Blue Dye | Detection Rate Sensitivity
      KOL-Index: 12712

      PURPOSE: The aim of this study was to evaluate the results of 10 years dynamic sentinel node biopsy experience in penile carcinoma at our institute.

      PATIENTS AND METHODS: 140 patients with clinically node-negative groins were prospectively included. Lymphoscintigraphy was performed after injection of 99mTechnetium-nanocolloid around the primary tumour. The sentinel node was intraoperatively identified with the aid of patent blue dye and a gamma ray detection probe. Lymph node dissection ...

      Known for Sentinel Node | Penile Carcinoma | Primary Tumour | Falsenegative Rate | Follow Studies
      KOL-Index: 12636

      PURPOSE: Time to progression (TTP), overall survival, and quality of life (QL) were compared in patients with hormone-resistant prostate cancer (HRPC) treated with prednisone (5 mg orally, four times a day) or flutamide (250 mg orally, three times a day).

      PATIENTS AND METHODS: Symptomatic patients were randomized to receive either prednisone (101 patients) or flutamide (100 patients). Subjective response was assessed based on performance status, the use of analgesics, and the need to ...

      Known for Prednisone Patients | Prostate Cancer | European Organization | Life Difference | Phase Iii

      Key People For Penile Cancer

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      #5
      Antonio Leopoldo Cubilla
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      Department of Urology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands | Netherlands Cancer Institute, Amsterdam, Netherlands; | Department of Urology, Netherlands Cancer Institute‐Antoni van Leeuwenhoek Hospita

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