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SJ Lee: Influence Statistics

BACKGROUND: The relationship between reproductive breast risk factors and breast cancer survival in patients with different breast cancer subtypes is not well known.

METHODS: We examined a large-sized, retrospective study of 23,882 subjects from the Korean Breast Cancer Registry. The breast cancer subtype was determined by immunohistochemical staining for estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 (HER2). Information regarding reproductive ...

Local anesthetics have been generally accepted as being safe. However, recent clinical trials and basic studies have provided strong evidence for the neurotoxicity of local anesthetics, especially through apoptosis. We hypothesized that local anesthetics cause neural complications through Schwann cell apoptosis. Among local anesthetics tested on the Schwann cell line, RT4-D6P2T, bupivacaine significantly induced cell death, measured by the methyl tetrazolium (MTT) assay, in a dose- (LD50 ...

Eugenol is a topical analgesic agent widely used in the dental clinic. To elucidate the molecular mechanism underlying its analgesic action, we investigated the effect of eugenol on high-voltage-activated calcium channel (HVACC) currents in dental primary afferent neurons, and with a heterologous expression system. Dental primary afferent neurons were identified by retrograde labeling with a fluorescent dye, DiI. Eugenol inhibited HVACC currents in both capsaicin-sensitive and ...

We report charge transport properties such as d.c. conductivity (σDC) and its temperature dependence for composites of poly(methyl methacrylate) (PMMA) and multiwalled carbon nanotubes (MWCNTs). The MWCNTs were synthesized through chemical vapor deposition with Fe or Co as catalyst. The MWCNTs were homogeneously dispersed in PMMA matrix through sonication to prepare MWCNT–PMMA composite films. We controlled mass concentration of MWCNTs in the composites, and the thickness of MWCNT–PMMA ...

Characterization of mercury emission and behavior from various stationary combustion processes were carried out for the major sources including coal-fired power plants and incinerators. Emission sampling and analysis of mercury at inlet and outlet of air pollution control devices (APCDs) for various sources have been made as the first attempt in Korea and now several institutions in governmental sectors are preparing the inventory on mercury.Speciation whether mercury forms are elemental ...

Turbulent bubbly air/water two-phase up and down flows in a circular test section were investigated. Important flow quantities such as local void fraction, liquid velocity and the Reynolds stresses were measured using both single-sensor and three-sensor hot-film anemometer probes. For up flows, it was found that the bubbles tended to migrate toward the wall and thus the void fraction profile showed a distinct peak near the wall. In contrast, for down flows, it was found that the bubbles ...

Eugenol, a natural capsaicin congener, is widely used in dentistry. Eugenol inhibits voltage-activated Na(+) and Ca(2+) channels in a transient receptor potential vanilloid 1 (TRPV1)-independent manner. We hypothesized that eugenol also inhibits voltage-gated K(+) currents, and investigated this in rat trigeminal ganglion neurons and in a heterologous system using whole-cell patch clamping. Eugenol inhibited voltage-gated K(+) currents, and the inhibitory effects of eugenol were observed ...

Given the flexible polishing effect in magnetic abrasive finishing (MAF), the precise and mirrorlike surface can be obtained during this process. However, the abrasives are easily flown away from the working area regardless of what abrasives are used in MAF; this situation will reduce the polished efficiency and induce the pollution problem in the environment. Besides, the abrasives cannot recycle after the finishing process. Therefore, a novel abrasive medium, using the silicone gel to ...

The effects of organoclay and polyhedral oligomeric silsesquioxanes (POSS) nanoparticles on the crystallization behavior of high molecular weight poly(ethylene terephthalate) (HMWPET; inherent viscosity of 1.05) were investigated in terms of nanoparticle content and shear rate. Both nanoparticles played a role of nucleating agent for PET and increased the cold crystallization temperature by about 24°C. The half-time of crystallization was also decreased with increasing the nanoparticle ...

AIM: To present the clinical and radiological follow-up results of coil embolization using the Enterprise stent for intracranial saccular aneurysms.

MATERIALS AND METHODS: The clinical and morphological outcomes of 261 consecutive patients with a total of 289 aneurysms that were treated with a stent-protected coiling technique using the Enterprise stent from June 2008 to August 2011 were assessed.

RESULTS: Stents were delivered before first coil insertion in 162 aneurysms (56.1%), during ...

Results are presented from searches for the standard model Higgs boson in proton–proton collisions at s=7 and 8 TeV in the Compact Muon Solenoid experiment at the LHC, using data samples corresponding to integrated luminosities of up to 5.1 fb−1 at 7 TeV and 5.3 fb−1 at 8 TeV. The search is performed in five decay modes: γγ, ZZ, W+W−, τ+τ−, and bb¯. An excess of events is observed above the expected background, with a local significance of 5.0 standard deviations, at a mass near 125 GeV, ...

The coupling and interactions between ship motion and inner-tank sloshing are investigated by a time-domain simulation scheme. For the time-domain simulation, the hydrodynamic coefficients and wave forces are obtained by a potential-thoery-based three-dimensional (3D) diffraction/radiation panel program in frequency domain. Then, the corresponding simulations of motions in time domain are carried out using convolution integral. The liquid sloshing in a tank is simulated in time domain by ...

Although eugenol is widely used in dentistry, little is known about the molecular mechanisms responsible for its anesthetic properties. In addition to calcium channels, recently demonstrated by our group, there could be another molecular target for eugenol. Using a whole-cell patch-clamp technique, we investigated the effect of eugenol on voltage-gated sodium channel currents (I(Na)) in rat dental primary afferent neurons identified by retrograde labeling with a fluorescent dye in ...

The use of high-intensity pulsed electric field (PEF) as a nonthermal method for triggering spore germination was investigated. Spores suspended in 0.01% NaCl solution (ca. 108cells/mL) were treated with an exponential-decay pulse (20–50 kV/cm) at selected temperatures. The inactivation resulting from the direct effect of PEF treatment was less than 0.5 log cycles, even with a relatively high electric field intensity of 40 kV/cm. Most of the surviving PEF-treated spores germinated after ...

This work is concerned with the development and application of ion implantation techniques for improving the corrosion resistance of zircaloy-4. The corrosion resistance in nitrogen implanted zircaloy-4 under a 120 keV nitrogen ion beam at an ion dose of 3 × 1017 cm−2 depends on the implantation temperature. The characteristics of surface oxidation and corrosion resistance were analyzed with the change of implantation temperature. It is shown that as implantation temperature rises from ...