Uterine Transplantation: Review of Livebirths and Reproductive Implications.: Influence Statistics

Expert Impact

Concepts for which they have has direct influence: Uterine transplantation , Transplantation utx , Transplant recipients , Organ transplantation , Pregnancy outcomes , Live birth , Reproductive outcomes .

Key People For Uterine Transplantation

Top KOLs in the world
#1
Mats Brännström
uterus transplantation nitric oxide insulin resistance
#2
Johan Mölne
uterus transplantation live birth hyperbaric oxygen therapy
#3
Cesar DIAZ‐GARCIA
uterus transplantation ovarian tissue fertility preservation
#4
Pernilla Dahm Kähler
uterus transplantation endometrial cancer live birth
#5
Liza Johannesson
uterus transplantation live birth vitro fertilization
#6
Andreas G Tzakis
liver transplantation fk 506 graft survival

Uterine Transplantation: Review of Livebirths and Reproductive Implications.

Abstract

. Uterine transplantation (UTx) is a fertility restoring treatment for women with absolute uterine factor infertility. At a time when there is no question of the procedure's feasibility, and as the number of livebirths begins to increase exponentially, various important reproductive, fetal, and maternal medicine implications have emerged. Detailed outcomes from 17 livebirths following UTx are now available, which are reviewed herein, along with contextualized extrapolation from pregnancy outcomes in other solid organ transplants. Differences in recipient demographics and reproductive aspirations between UTx and other transplant recipients make extrapolating management strategies and outcomes in other solid organ transplants inappropriate. Whereas preterm delivery remains prominent, small for gestational age or hypertensive disorders do not appear to be as prevalent following UTx when compared to other solid organ transplants. Given the primary objective of undertaking UTx is to achieve a livebirth, publication of reproductive outcomes is essential at this early stage, to reflect on and optimize the management of future cases.