• KOLs
  • Weight Gain
  • Variação De Peso De...

Variação de peso de usuárias de acetato de medroxiprogesterona de depósito segundo índice de massa corporal em seguimento de seis anos: Influence Statistics

Expert Impact

Concepts for which they have has direct influence: Weight gain , Dmpa users , Normal weight , Medroxyprogesterone acetate , Acetate dmpa , Retrospective studies , Factors weight .

Key People For Weight Gain

Top KOLs in the world
#1
Walter Churchill Willett
breast cancer type 2 diabetes coronary heart disease
#2
Katherine M Flegal
united states prevalence obesity blood lead levels
#3
Graham A Colditz
breast cancer physical activity united states
#4
Jo Ann E Manson
breast cancer postmenopausal women type 2 diabetes
#5
David B Allison
weight loss body composition united states
#6
Frank B Hu
type 2 diabetes cardiovascular disease physical activity

Variação de peso de usuárias de acetato de medroxiprogesterona de depósito segundo índice de massa corporal em seguimento de seis anos

Abstract

. PURPOSE: To determine weight variation in women with different Body Mass Index (BMI) in use of trimestral injections of depot-medroxyprogesterone acetate (DMPA), and compare it to women users of a non-hormonal method. METHODS: Retrospective study with the chart review of 226 DMPA users and 603 controls, users of DIU TCu380A. Women were distributed in categories, according to their initial BMI, as having normal weight (<25 kg/m(2)), overweight (25 to 29,9 kg/m(2)) and being obese (>or=30 kg/m(2)), and were followed-up for six years, with yearly measurements of weight and BMI. The statistic test ANOVA was used to measure the weight variation among the groups in each BMI category every year. RESULTS: The average age at the onset of the method employed was higher in the study group than in the controls, in all the BMI categories: 31.6+/-SD 7.1 X 27.4+/-SD 5.5 in the normal weight category (p<0.0001); 37.3+/-SD 6.8 X 29.2+/-SD 6.0 in the overweight category (p<0.0001); and 35.3+/-SD 6.4 X 29.7+/-SD 5.8 among obese women (p<0.0001). DMPA users showed weight increase as compared to the controls in the overweight category (p=0.0082); and the weight increase along the observation period was also higher among the DMPA users than among the controls, for the normal weight (p<0.0001) and overweight (p=0.0008) categories. In the obese group, there was no BMI variation between the groups, nor along the period during which they were using the method. CONCLUSIONS: There was no change in weight gain among DMPA users from the obese category. Prospective studies should be done with metabolic tests to establish the determining factors of weight gain in normal and overweight women.