• Breast Approach
    • Zhiyu Li
    • Zhiyu Li: Influence Statistics

      Zhiyu Li

      Zhiyu Li

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      Beijing Digestive Disease Center, Beijing, Peking, China. | Chinese Academy of Sciences Center for Excellence in Quaternary Science and Global Change, Xi’an 710061, China | ...

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      Zhiyu Li:Expert Impact

      Concepts for whichZhiyu Lihas direct influence:Breast approach,Bacillus phytases,Lateral neck dissection,Protein hydrolysates,Electronic tongue,Laser shock,Laser shock peening,Colorectal liver metastases.

      Zhiyu Li:KOL impact

      Concepts related to the work of other authors for whichfor which Zhiyu Li has influence:Endoscopic thyroidectomy,Bioactive peptides,Neisseria gonorrhoeae,Neck dissection,Sodium borohydride,Chemical reduction,Helicobacter pylori.

      KOL Resume for Zhiyu Li


      Beijing Digestive Disease Center, Beijing, Peking, China.

      Chinese Academy of Sciences Center for Excellence in Quaternary Science and Global Change, Xi’an 710061, China


      College of Food Science and Technology, Nanjing Agricultural University, 1 Weigang Road, Nanjing 210095, China.

      School of Environmental Science and Engineering/State Key Lab of Engines, Tianjin University, Tianjin, 300072, China

      a Civil and Environmental Engineering, Brigham Young University, Provo, UT, USA, View further author information


      National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

      School of Agricultural Engineering and Food Science, Shandong University of Technology, Zibo, China


      Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Baojian Road, 150086, Harbin, China


      School of Information, Renmin University of China, Beijing, China

      Novilytic, Kurz Purdue Technology Center (KPTC), 1281 Win Hentschel Boulevard, West Lafayette, Indiana, 47906, United States


      University of California Berkeley School of Law, Berkeley, USA

      Technology Center, Kunming, China


      College of Automation, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China, nuaa.edu.cn

      Department of Microbiology, Key Laboratory for Experimental Teratology of Chinese Ministry of Education, School of Medicine, Shandong University, Jinan, Shandong 250012, People’s Republic of China


      Flavors and Fragrance Technical Center of Hongta Tobacco (Group) Co., Ltd., 653100, Yuxi, China

      Department of Process Engineering and Applied Science, Dalhousie University, P.O. Box 15000, Halifax Nova Scotia B3H 4R2, Canada


      Military Sports Brigade of People's Liberation Army, Beijing 100072, China


      University of the Sciences, Department of Pharmaceutical Sciences, 600 S 43rd Street, Philadelphia, PA 19104, USA


      Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, P.R. China


      Department of General Surgery, Second Affiliated Hospital, Zhejiang University, 310009, Hangzhou, China


      College of Animal Science, Zhejiang University, 310029, Hangzhou, People’s Republic China


      Northwestern Polytech. Univ., Xian


      Department of Electronic Engineering, Beijing Institute of Technology, Beijing, 100081, China


      a Department of Medicinal Chemistry , China Pharmaceutical University , Nanjing, 210009, P.R. China

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      Sample of concepts for which Zhiyu Li is among the top experts in the world.
      Concept World rank
      ppp5c expression #4
      issue commit #4
      expression ppp5c #5
      borohydride aqueous solution #6
      knockdown ppp5c #8
      ppp5c knockdown #9
      preoperative testing markers #9
      bmp2 dimer #15
      bacillus phytases #15
      barley noodles #18
      pylori periodontal #19
      neck endoscopic #22
      deeplink #22
      commit issue #23
      neisseria gyra #23
      incorporating preoperative #26
      ptc female #26
      04 chitosan #26
      ppp5c #32
      approach papillary #34
      unsightly scar #35
      phytate complex #35
      dimer proteins #36
      thyroidectomy breast #38
      eeg based brain #43
      uwb kalman #45
      eeg motor imagery #53
      follow cosmetic #53
      skin inspection #58
      detection quinolone #61
      endoscopic lateral #71
      aqueous solution preparation #80
      breast approach #86
      intersection analysis #88
      dissection ptc #92
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      Prominent publications by Zhiyu Li

      KOL-Index: 12124

      BackgroundTraditional open surgery for lateral neck dissection for patients with papillary thyroid carcinoma (PTC) requires a large incision to obtain adequate exposure of the surgical field, leaving an unsightly scar. We applied scarless (in the neck) endoscopic thyroidectomy (SET) via breast approach to lateral neck dissection for PTC and evaluated its feasibility and safety.MethodsBetween July 2007 and October 2009, 11 T1 (tumor size not exceeding 2 cm) low-risk PTC female patients ...

      Known for Breast Approach | Neck Dissection | Papillary Thyroid | Preliminary Report | Endoscopic Lateral
      KOL-Index: 8298

      Helicobacter pylori (H. pylori), a pathogen inducing peptic disease, is recently found to be binding to the progress of periodontitis. Most previous studies are case-controlled, and they investigate the risk of H. pylori infection in disease the development of while few studies evaluate the correlation between H. pylori and periodontal pathogens. Therefore, we investigated the correlation between H. pylori infection with periodontal parameters, periodontal pathogens and inflammation. The ...

      Known for Pylori Infection | Periodontal Pathogens | Chronic Periodontitis | Prevotella Intermedia | Porphyromonas Gingivalis
      KOL-Index: 7085

      Ser/Thr protein phosphatase 5 (PPP5C) has been reported to participate in tumor progression. However, its functional role in hepatocellular carcinoma (HCC) remains unknown yet. In this study, we firstly evaluated the expression levels of PPP5C in six HCC cell lines by real-time PCR and found that PPP5C was widely expressed in HCC cells. To explore the role of PPP5C in HCC cell growth, lentivirus-mediated short hairpin RNA (shRNA) was employed to silence PPP5C expression in HepG2 and ...

      Known for Hepatocellular Carcinoma | Hcc Cells | Knockdown Ppp5c | Functional Role | Thr Protein Phosphatase
      KOL-Index: 6726

      Afluorometric real-time polymerase chain-reaction (PCR)-hybridization system, the LightCycler was developed for the detection of Neisseria gonorrhoeae in clinical samples and the analysis of point mutations associated with quinolone resistance in the gyrAgene. This system allowed us to amplify the N. gonorrhoeae-specific gyrA gene from an amount of DNA corresponding to five genome copies per reaction. We were able to detect N. gonorrhoeae in either 55 control strains or 36 nonisolated ...

      Known for Quinolone Resistance | Rapid Detection | Neisseria Gonorrhoeae | Gyra Gene | Reaction Sensitivity
      KOL-Index: 6459

      BackgroundLong non-coding RNA H19 (H19) plays an important role by regulating protein expression in different tissues and organs of the body. However, whether H19 induces hypoxia/reoxygenation (h/R) injury via increase of autophagy in the hepatoma carcinoma cells is unknown.ResultsH19 was expressed in the hepatoma carcinoma cells (Hep G2 and HCCLM3 cells) and its expression was most in 8 h/24R. The knockdown of H19 and 3-MA (an autophagy inhibitor) protected against h/R-induced ...

      Known for Coding Rna | Akt Mtor | Reoxygenation Injury | Protein Expression | Hepatocellular Humans
      KOL-Index: 4726

      A major challenge in motor imagery (MI) of electroencephalogram (EEG) based brain–computer interfaces (BCIs) is the individual differences for different people. That the classification model should be retrained from scratch for a new subject often leads to unnecessary time consumption. In this paper, a “brain-ID” framework based on the hybrid deep neural network with transfer learning (HDNN-TL) is proposed to deal with individual differences of 4-class MI task. An end-to-end HDNN is ...

      Known for Transfer Learning | Motor Imagery | Neural Network | Hybrid Deep | Classification Performance
      KOL-Index: 4701

      Refolding is often the bottle-neck step in producing recombinant proteins from inclusion bodies of Escherichia coli, especially for dimer proteins. The refolding process is protein specific, engaging a lot of time and cost to optimize conditions so that the thermodynamics favor protein refolding over competitive aggregation. Bone morphogenetic protein-2 (BMP-2) is a potent osteogenic agent having significant applications in bone regeneration therapy. In this study, we present a novel ...

      Known for Bone Morphogenetic | Recombinant Proteins | Protein Refolding | Inclusion Bodies | Cation Exchange
      KOL-Index: 4628

      A nano-encapsulation strategy for a chitosan-coated liposomal oral delivery system using milk fat globule membrane (MFGM) phospholipids for the entrapment of antidiabetic peptides prepared from Atlantic salmon (Salmo salar) protein hydrolysates (SPH) was developed. The size, zeta potential, entrapment efficiency, stability during freeze-drying freeze thawing, and long-term storage abilities of the nano-capsules were investigated as a function of concentrations of phospholipid and ...

      Known for Protein Hydrolysates | Chitosan Coating | Entrapment Efficiency | Zeta Potential | Physical Stability
      KOL-Index: 4217

      BACKGROUND: This study aimed to investigate the predictive significance of preoperative red cell volume distribution width (RDW) level for prognosis and to establish nomograms incorporating preoperative blood markers to predict postoperative complications and survival in patients with colorectal liver metastases (CRLM).

      METHODS: This retrospective study included 380 enrolled CRLM patients who underwent hepatic resection. Predictors of postoperative complications were explored using ...

      Known for Colorectal Liver Metastases | Crlm Patients | Optimal Cutoff Point | Incorporating Preoperative | Postoperative Complications
      KOL-Index: 4088

      BACKGROUND: The novel coronavirus disease 2019 (COVID-19) broke out globally. Early prediction of the clinical progression was essential but still unclear. We aimed to evaluate the timeline of COVID-19 development and analyze risk factors of disease progression.

      METHODS: In this retrospective study, we included 333 patients with laboratory-confirmed COVID-19 infection hospitalized in the Third People's Hospital of Shenzhen from 10 January to 10 February 2020. Epidemiological feature, ...

      Known for Clinical Progression | Coronavirus Disease Covid19 | Early Prediction | Pandemics Pneumonia | Factors Sars
      KOL-Index: 3878

      AIM: To investigate cyclo (Arg-Gly-Asp-D-Phe-Lys) peptide (RGD)-modified PEGylated dendrimer-entrapped gold nanoparticles (PEGylated Au DENPs-RGD) for targeted computed tomography (CT) imaging of breast carcinomas.

      MATERIALS & METHODS: PEGylated Au DENPs-RGD were synthesized and characterized. Then, the PEGylated Au DENPs-RGD for targeted CT imaging were investigated using the MDA-MB-435 cell line, an integrin-rich breast carcinoma cells, and mice with MDA-MB-435 xenograft tumors. ...

      Known for Tomography Imaging | Pegylated Dendrimer | Gold Nanoparticles | Ray Computed | Integrin Receptors
      KOL-Index: 3841

      The COVID-19 pandemic has accounted for millions of infections and hundreds of thousand deaths worldwide in a short-time period. The patients demonstrate a great diversity in clinical and laboratory manifestations and disease severity. Nonetheless, little is known about the host genetic contribution to the observed interindividual phenotypic variability. Here, we report the first host genetic study in the Chinese population by deeply sequencing and analyzing 332 COVID-19 patients ...

      Known for Host Genetic | Covid19 Severity | Chinese Population | Tmprss2 Protein | Worst Outcome
      KOL-Index: 3532

      BACKGROUND AND PURPOSE: Disturbed flow induces endothelial dysfunction and contributes to uneven distribution of atherosclerotic plaque. Emerging evidence suggests that harmine, a natural constituent of extracts of Peganum harmala, has potent beneficial activities. Here, we investigated if harmine has an atheroprotective role under disturbed flow and the underlying mechanism.

      EXPERIMENTAL APPROACH: Mice of ApoE-/- , LDLR-/- , and endothelial cell (EC)-specific overexpression of ...

      Known for Yesassociated Protein | Endothelial Cell | Harmine Alleviated | Atherosclerotic Lesion | Inflammatory Response
      KOL-Index: 3192

      Phytases are a special class of phosphatases that catalyze the sequential hydrolysis of phytate to less-phosphorylated myo-inositol derivatives and inorganic phosphate. Bacillus phytases, which exhibit their desirable activity profile under neutral pH, higher thermal stability, and strict substrate specificity for the calcium–phytate complex, have considerable potential in commercial and environmental applications. This review describes recent findings concerning the production, ...

      Known for Bacillus Phytases | Inorganic Phosphate | Biochemical Properties | Animal Nutrition | Human Health
      KOL-Index: 2620

      Links between issue reports and corresponding code commits to fix them can greatly reduce the maintenance costs of a software project. More often than not, however, these links are missing and thus cannot be fully utilized by developers. Current practices in issue-commit link recovery extract text features and code features in terms of textual similarity from issue reports and commit logs to train their models. These approaches are limited since semantic information could be lost. ...

      Known for Deep Learning | Knowledge Graph | Issue Reports | Source Code | Art Method

      Key People For Breast Approach

      Top KOLs in the world
      Yeo K MD YOUN
      breast cancer endoscopic thyroidectomy thyroid surgery
      Jun Ho Choe
      papillary thyroid breast cancer lymph node
      Seung Keun Oh
      breast cancer endoscopic thyroidectomy cell lines
      Ki Wook Chung
      papillary thyroid distant metastasis active surveillance
      Kyoung Sik Park
      endoscopic thyroidectomy breast cancer ras mutations
      Seok Won Kim
      breast cancer neoadjuvant chemotherapy bone cement

      Beijing Digestive Disease Center, Beijing, Peking, China. | Chinese Academy of Sciences Center for Excellence in Quaternary Science and Global Change, Xi’an 710061, China | Key Laboratory of Aerosol Chemistry and Physics, State Key Laboratory of Loes

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