KOLFlecainide
Who are the top experts researching the use of flecainide?
The top experts researching flecainide are: Alan John Camm, Kosuke Doki and Kevin J. Hellestrand.
What are the top concepts researched in studies about flecainide?
The most researched concepts in studies of flecainide are: Atrial Fibrillation, Ventricular Tachycardia, Antiarrhythmic Drugs, Sinus Rhythm, Heart Rate, Coronary Artery, Myocardial Infarction, Sudden Cardiac and Catheter Ablation.
Recent articles about Flecainide
Flecainide
.. Synopsis: Flecainide1 is a Class I antiarrhythmic drug of the local anaesthetic type. It can be given either intravenously or orally and its pharmacokinetic properties allow relatively ...
Known for Flecainide Patients | Antiarrhythmic Agents | Oral Administration | Ventricular Tachycardia Reentrant Arrhythmias In The Subacute Infarction Period. The Proarrhythmic Effect...
.. that flecainide was associated with an increased incidence of sudden cardiac death in postinfarction patients. The exact mechanism(s) of the proarrhythmic effects of flecainide remain ...
Known for Reentrant Arrhythmias | Proarrhythmic Effects | Myocardial Infarction | Coronary Artery | Ventricular Tachycardia Antiarrhythmic And Electrophysiologic Effects Of Flecainide On Acutely Induced...
.. of flecainide to treat AF in horses have produced conflicting results, and the antiarrhythmic mechanisms of flecainide are not fully understood.
OBJECTIVES: To study the potential of ...
Known for Atrial Fibrillation | Acutely Induced | Duration Vulnerability | Healthy Horses | Ventricular Depolarization Flecainide Toxicity: Reversal Of Drug Effects By Isoproterenol Infusion
.. of Flecainide Toxicity by Isoproterenol.Introduction: Toxic levels of flecainide can cause life-threatening electrophysiologic and hemodynamic changes. Isoproterenol is known to reverse ...
Known for Flecainide Toxicity | Beta Blockade | Isoproterenol | Reversal | Conduction Flecainide Distribution, Transplacental Passage, And Accumulation In The Amniotic...
.. of flecainide acetate and its transplacental passage (both into the fetus and in the amniotic fluid) during the third trimester of pregnancy.
DATA SOURCES: Reference articles and books are ...
Known for Amniotic Fluid | Gestational Age | Maternal Fetal | Flecainide Humans | Trimester Pregnancy Ryr2 Channel Inhibition Is The Principal Mechanism Of Flecainide Action In Cpvt
.. drug flecainide prevents ventricular tachyarrhythmia in patients with catecholaminergic polymorphic ventricular tachycardia (CPVT), a disease caused by hyperactive RyR2 (cardiac ryanodine ...
Known for Flecainide Action | Principal Mechanism | Ventricular Tachycardia | Release Channel | Sarcoplasmic Reticulum Electrophysiological Effects Of The Combination Of Mexiletine And Flecainide In...
.. of flecainide alone, mexiletine alone and their combination at the Na+ channel level were studied in guinea-pig papillary muscles. The maximum upstroke velocity (Vmax) was used as an ...
Known for Electrophysiological Effects | Vmax Block | Ventricular Fibres | Papillary Muscles | Maximum Upstroke Velocity Safety And Efficacy Of Flecainide In Subjects With Long Qt‐3 Syndrome (Δkpq...
.. with flecainide versus placebo in a small group of LQT-3 patients with the DeltaKPQ deletion to evaluate the safety and efficacy of flecainide in this genetic disorder. In vitro studies ...
Known for Long Qt | Genetic Disorder | Flecainide Therapy | Deltakpq Mutation | Syndrome Male Effect Of Flecainide Derivatives On Sarcoplasmic Reticulum Calcium Release...
.. PURPOSE: Flecainide is a use-dependent blocker of cardiac Na(+) channels. Mechanistic analysis of this block showed that the cationic form of flecainide enters the cytosolic vestibule of ...
Known for Sarcoplasmic Reticulum | Cardiac Ryanodine Receptor | Calcium Release | Ryr2 Channels | Channel Block Intravenous Drug Challenge Using Flecainide And Ajmaline In Patients With Brugada Syndrome
.. intravenous flecainide and ajmaline with respect to their ability to induce or accentuate the typical ECG pattern of Brugada syndrome.
BACKGROUND: Brugada syndrome is associated with a ...
Known for Brugada Syndrome | Ajmaline Patients | Precordial Leads | Intravenous Drug Challenge | Positive Response