KOLMetolazone
Who are the top experts researching the use of metolazone?
The top experts researching metolazone are: Andrew Whelton, R J Kellett and Jules B. Puschett.
What are the top concepts researched in studies about metolazone?
The most researched concepts in studies of metolazone are: Diuretic Therapy, Swelling, Blood Pressure, Renal Function, Liquid Chromatography, Acute Heart, Sodium Excretion, Mass Spectrometry, Chronic Kidney and Essential Hypertension.
Recent articles about Metolazone
Combination Therapy With Metolazone And Loop Diuretics In Outpatients With...
Metolazone is a potent thiazide-like diuretic. It is recommended in severe congestive heart failure (HF). We conducted a review of the existing literature and found that the available ...
Known for Loop Diuretics | Combination Therapy | Refractory Heart Failure | Blood Pressure | Diuretic Response Metolazone And Its Role In Edema Management
Metolazone is commonly administered in conjunction with a loop diuretic to manage volume overload in patients otherwise resistant to loop diuretic therapy alone. Metolazone is a thiazide-type ...
Known for Metolazone Loop | Diuretic Therapy | Volume Overload | Furosemide Heart | Edema Cardiac Validated Rp-Hplc Method For Simultaneous Quantitation Of Losartan Potassium And...
.. and Metolazone in formulation. This method is based on a HPLC separation of the two drugs on the Thermo Hypersil BDS-C(18) (250 mm × 4.6 mm, 5.0 μm) with isocratic conditions and a simple ...
Known for Losartan Potassium | Hplc Method | Simultaneous Determination | Flow Rate | Concentration Range Metolazone And Bendroflumethiazide In Hypertension: Physiologic And Metabolic Observations
.. mg metolazone and 5 mg bendroflumethiazide on blood pressure and metabolic parameters. After a 4-wk run-in placebo period, patients received either metolazone or bendroflumethiazide for 6 ...
Known for Potassium Supplements | Hypertensive Patients | Male Metolazone | Total Body Development Of A Lc–ms/ms-Based Method For Determining Metolazone Concentrations...
.. of metolazone in human plasma samples. This method involves high-performance liquid chromatography coupled with tandem mass spectrometry and is more sensitive, selective and rapid than ...
Known for Pharmacokinetic Study | Internal Standard | Mass Spectrometry | Validated Method | Human Plasma Efficacy Of Intravenous Chlorothiazide For Refractory Acute Decompensated Heart...
.. to metolazone.
DESIGN: Retrospective cohort study with patients serving as their own controls.
SETTING: Large, academic, tertiary care hospital.
PATIENTS: Forty-five patients with ADHF who ...
Known for Intravenous Chlorothiazide | Heart Failure | Patients Adhf | Acute Decompensated | Loop Diuretics Pharmacokinetic And Pharmacodynamic Interaction Between Furosemide And Metolazone In Man
.. of metolazone. The mechanism of this additive effect is unclear. The purpose of the present investigation was to establish whether metolazone changes the pharmacokinetics of furosemide and ...
Known for Pharmacokinetics Furosemide | Diuretics Drug | Diuretic Combination | Treatment Metolazone | Sodium Chloride Determination Of Metolazone In Human Blood By Liquid Chromatography With...
.. of metolazone in human blood. Metolazone was extracted from blood using ethyl acetate and separated on a C18 column interfaced with a triple quadrupole tandem mass spectrometer. The mobile ...
Known for Liquid Chromatography | Mass Spectrometry | Determination Metolazone | Pharmacokinetic Study | Mobile Phase Efficacy And Safety Of Intravenous Chlorothiazide Versus Oral Metolazone In...
.. oral metolazone when added to loop diuretics in patients with acute decompensated heart failure (ADHF) and loop diuretic resistance.
DESIGN: Retrospective cohort study.
SETTING: Large ...
Known for Oral Metolazone | Diuretic Resistance | Intravenous Chlorothiazide | Heart Failure | Renal Function Addition Of Metolazone To Overcome Tolerance To Furosemide In Infants With...
.. diuretic metolazone, in combination with furosemide, would inhibit water and electrolyte reabsorption and overcome pharmacologic tolerance to furosemide alone. Infants with ...
Known for Bronchopulmonary Dysplasia | Furosemide Metolazone | Urinary Excretion | Sodium Chloride | Drug Tolerance