Recent articles about Urea Cycle Disorder

A Phase 2, Open-Label Study To Evaluate The Efficacy And Safety Of Kb195 In...

[ CLINICAL_TRIAL ] ... a Urea Cycle Disorder with Inadequate Control on Standard of Care Detailed Description We expect the trial to enroll approximately 24 Urea Cycle Disorder (UCD) patients on standard of care ...
Known for
Cycle Disorder | Trial Kb195 | Evaluate Safety | Unlocked Phase

Longitudinal Study Of Urea Cycle Disorders. Longitudinal Study Of Urea Cycle Disorders.

[ CLINICAL_TRIAL ]
Known for
Urea Cycle | Disorders Ucd | Rare Inherited | Months Psychological

A Randomised, Controlled, Open-Label Parallel Arm Study Of Safety, Pk And Ammonia...

[ CLINICAL_TRIAL ] ... in urea cycle disorder subjects not currently or previously chronically treated with phenylacetic acid (phenylacetate; PAA) prodrugs. The study design will include: 1) Baseline Period; 2) ...
Known for
Urea Cycle | Parallel Arm | Glycerol Phenylbutyrate | Period Ravicti

Pilot Study: Urea Cycle Disorders Practice Patterns And Outcomes Assessment....

[ CLINICAL_TRIAL ] ... of Urea Cycle Disorders" are different than participants in the Urea Cycles Disorders Consortium (UCDC) Rare Diseases Clinical Research Network (RDCRN) Contact Registry and to determine if ...
Known for
Urea Cycle | Disorders Ucdc | Web Portal | Contact Registry

Noninvasive Biomarkers Of Hepatic Fibrosis In Urea Cycle Disorders. Liver Disease...

[ CLINICAL_TRIAL ] ... with urea cycle disorders (UCDs) using serum biomarkers, Fibroscan, and MRE. This study will be conducted at 5 sites of the Urea Cycle Disorders Consortium: Baylor College of Medicine in ...
Known for
Hepatic Fibrosis | Cycle Disorders | Liver Ucds | Serum Biomarkers

The Nih Uni Study: Urea Cycle Disorders, Nutrition And Immunity. The Nih Uni...

[ CLINICAL_TRIAL ] ... with urea cycle disorders.To study how people with urea cycle disorders and healthy volunteers respond to standard flu and/or hepatitis A vaccines.To compare differences in nutrition and ...
Known for
Urea Cycle | Nih Uni | Immune Deficiencies | Ucd Disorders

Assessment Of A Breath Ammonia Monitoring Device For Its Potential To Improve The...

[ CLINICAL_TRIAL ] ... aims Urea cycle disorders are a group of genetic metabolic conditions that prevents correct conversion of nitrogen to urea and, instead, produces ammonia. These patients cannot effectively ...
Known for
Breath Ammonia | Urea Cycle | Monitoring Device | Involves Children

Open, Prospective, Diagnostic, Multicentre Study In Healthy Subjects, Patients...

[ CLINICAL_TRIAL ] ... the urea cycle in healthy subjects, asymptomatic carriers of Urea Cycle Disorders (UCD) mutations and subjects with genetically proven urea cycle disorders. The ureagenesis rate will be ...
Known for
Urea Cycle | Ucd Mutations | Single Application | Asymptomatic Carriers

A Pharmacokinetic Study Of Sodium Phenylbutyrate In Urea Cycle Disorder. A...

[ CLINICAL_TRIAL ] ... in urea cycle disorder. To clarify pharmacokinetic properties of sodium phenylbutyrate and its metabolites in urea cycle disorder
Known for
Sodium Phenylbutyrate | Cycle Disorder | Pharmacokinetic Properties | Metabolites Urea

Oxidative Stress, Inflammation And Acute Decompensation In Urea Cycle Disorders....

[ CLINICAL_TRIAL ] ... with urea cycle disorders suffer episodes of periodic hyperammonemic crisis, often in association with intercurrent infections. The immediate cause of this decompensation is the increase in endo
Known for
Oxidative Stress | Urea Cycle | Acute Decompensation | Baseline Decompensated

 

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