• Disease
  • Intracranial
  • Intracranial Hypertension
  • Valérie Biousse

    Prominent publications by Valérie Biousse

    KOL Index score: 14662

    PURPOSE: Obesity and weight gain are known risk factors for idiopathic intracranial hypertension (IIH; or pseudotumor cerebri). The authors examined profiles of body mass index (BMI) and patterns of weight gain associated with IIH. They also examined vision-specific health-related quality of life (HRQOL) in newly diagnosed IIH patients and explored the relative contribution of obesity and weight gain to overall HRQOL in this disorder.

    DESIGN: Matched case-control study.

    METHODS: Female ...

    Also Ranks for: Weight Gain |  pseudotumor cerebri |  iih life |  body mass bmi |  cerebrospinal fluid pressure
    KOL Index score: 13316

    INTRODUCTION: Idiopathic intracranial hypertension (IIH) is increasingly recognized as a cause of spontaneous cerebrospinal fluid (CSF) leak in the otolarnygological and neurosurgical literature. The diagnosis of IIH in patients with spontaneous CSF leaks typically is made a few weeks after surgical repair of the leak when symptoms and signs of elevated intracranial pressure (ICP) appear.

    METHODS: Case reports and literature review. Two young obese women developed spontaneous CSF ...

    Also Ranks for: Csf Leak |  cerebrospinal fluid |  intracranial hypertension |  icp patients |  literature review
    KOL Index score: 11870

    PURPOSE: To determine medical student preferences for learning the ocular fundus examination and to assess their accuracy using different examination modalities.

    DESIGN: Prospective, randomized study of medical student education approaches.

    METHODS: First-year medical students received training in direct ophthalmoscopy using simulators and human volunteers. Students were randomized to receive vs not receive specific training on interpreting fundus photographs prior to accuracy ...

    Also Ranks for: Medical Students |  direct ophthalmoscopy |  ocular fundus |  totems study |  physical examination
    KOL Index score: 11482

    PURPOSE: To use static threshold perimetry to examine the stages of improvement and the potential for late improvement of visual fields after surgical resection of pituitary adenomas causing visual loss from compression of the anterior visual pathways.

    METHODS: Retrospective review of charts of patients with pituitary tumors and abnormal static threshold perimetry before or soon after treatment who had subsequent visual fields. Quantification of the visual field mean deviation overall, ...

    Also Ranks for: Visual Fields |  pituitary tumor resection |  1 week |  relative improvement |  2 years
    KOL Index score: 11198

    BACKGROUND: Acute isolated optic neuritis is often the first manifestation of multiple sclerosis (MS), and its management remains controversial. Over the past decade, with the advent of new disease-modifying agents, management of isolated optic neuritis has become more complicated.

    OBJECTIVES: To evaluate the current practice patterns of Canadian ophthalmologists and neurologists in the management of acute optic neuritis, and to evaluate the impact of recently published randomized ...

    Also Ranks for: Optic Neuritis |  neurologists ophthalmologists |  management acute |  multiple sclerosis |  magnetic resonance imaging
    KOL Index score: 11097

    BACKGROUND: Nonophthalmologist physicians do not confidently perform direct ophthalmoscopy. The use of artificial intelligence to detect papilledema and other optic-disk abnormalities from fundus photographs has not been well studied.

    METHODS: We trained, validated, and externally tested a deep-learning system to classify optic disks as being normal or having papilledema or other abnormalities from 15,846 retrospectively collected ocular fundus photographs that had been obtained with ...

    Also Ranks for: Fundus Photographs |  artificial intelligence |  sensitivity specificity |  papilledema abnormalities |  deep learning
    KOL Index score: 10964

    BACKGROUND: The association between cerebrospinal fluid (CSF) leaks at the skull base and raised intracranial pressure (ICP) has been reported since the 1960s. It has been suggested that spontaneous CSF leaks might represent a variant of idiopathic intracranial hypertension (IIH). We review the evidence regarding the association between spontaneous CSF leaks and IIH, and the role of ICP in the pathophysiology of nontraumatic skull base defects. We also discuss the management of ICP in ...

    Also Ranks for: Intracranial Hypertension |  cerebrospinal fluid |  skull base |  spontaneous csf leaks |  patients iih
    KOL Index score: 10736

    STUDY OBJECTIVE: During the first phase of the Fundus Photography vs Ophthalmoscopy Trial Outcomes in the Emergency Department study, 13% (44/350; 95% confidence interval [CI] 9% to 17%) of patients had an ocular fundus finding, such as papilledema, relevant to their emergency department (ED) management found by nonmydriatic ocular fundus photography reviewed by neuro-ophthalmologists. All of these findings were missed by emergency physicians, who examined only 14% of enrolled patients ...

    Also Ranks for: Fundus Photography |  emergency physicians |  nonmydriatic ocular |  direct ophthalmoscopy |  sensitivity 95
    KOL Index score: 10578

    BACKGROUND: Obstructive sleep apnea (OSA) may be associated with idiopathic intracranial hypertension (IIH), a disorder most commonly occurring in young obese women. Because polysomnography, the standard test for diagnosing OSA, is expensive and time consuming, questionnaires have been developed to identify persons with OSA. The Berlin questionnaire (BQ) reliably identifies middle-aged and older persons in the community who are at high-risk for OSA. We aimed to validate the BQ as a ...

    Also Ranks for: Sleep Apnea |  berlin questionnaire |  osa polysomnography |  iih patients |  intracranial hypertension
    KOL Index score: 10376

    PURPOSE: To evaluate the efficacy of a single intravitreal injection of rAAV2/2-ND4 in subjects with visual loss from Leber hereditary optic neuropathy (LHON).

    DESIGN: RESCUE is a multicenter, randomized, double-masked, sham-controlled, phase 3 clinical trial.

    PARTICIPANTS: Subjects with the m.11778G>A mitochondrial DNA mutation and vision loss ≤6 months from onset in 1 or both eyes were included.

    METHODS: Each subject's right eye was randomly assigned (1:1) to treatment with rAAV2/2-ND4 ...

    Also Ranks for: Leber Hereditary |  raav2 2nd4 |  intravitreal gene therapy |  vision loss |  treated eyes
    KOL Index score: 9910

    BACKGROUND: The primary role of brain imaging in idiopathic intracranial hypertension (IIH) is to exclude other pathologies causing intracranial hypertension. However, subtle radiologic findings suggestive of IIH have emerged with modern neuroimaging. This review provides a detailed description of the imaging findings reported in IIH and discusses their possible roles in the pathophysiology and the diagnosis of IIH.

    EVIDENCE ACQUISITION: References were identified by searches of PubMed ...

    Also Ranks for: Intracranial Hypertension |  imaging findings iih |  pseudotumor cerebri |  optic nerve |  computed tomography
    KOL Index score: 9800

    PURPOSE: To test a topical agent with purported antiapoptotic properties as prophylactic treatment after first eye involvement in Leber hereditary optic neuropathy (LHON), a maternally-inherited disorder characterized by bilateral, often sequential, visual loss.

    DESIGN: Open labeled, nonrandomized prospective pilot study.

    METHODS: Nine primary mutation molecularly confirmed LHON patients with one eye vision loss for less than 6 months and normal visual function in the fellow eye were ...

    Also Ranks for: Eye Involvement |  leber hereditary |  optic neuropathy |  visual acuity |  topical brimonidine purite
    KOL Index score: 9739

    Sneddon syndrome is characterized by the association of livedo reticularis and cerebral ischemic arterial events (stroke or transient ischemic attack). Reported prevalence of antiphospholipid antibodies is highly variable. We conducted this study to compare the clinical and pathologic features of patients with Sneddon syndrome according to the presence or absence of antiphospholipid antibodies. Forty-six consecutive patients with Sneddon syndrome were analyzed. All were examined by the ...

    Also Ranks for: Antiphospholipid Antibodies |  sneddon syndrome |  livedo reticularis |  lupus anticoagulant |  skin biopsy
    KOL Index score: 9736

    BACKGROUND AND PURPOSE: Cerebral infarction is the most frequent and severe manifestation of extracranial internal carotid artery dissection. However, few data exist on the precise time course of symptoms preceding the onset of stroke.

    METHODS: We studied 80 consecutive patients (29 retrospectively, 51 prospectively) with angiographically diagnosed extracranial internal carotid artery dissection and, during a 6-month follow-up, recorded the time elapsed between the onset of the first ...

    Also Ranks for: Carotid Artery |  stroke patients |  local signs |  symptoms onset |  cerebral infarction


    Valérie Biousse: Influence Statistics

    Sample of concepts for which Valérie Biousse is among the top experts in the world.
    Concept World rank
    development aidls #1
    crao eye stroke #1
    3353 43 #1
    iih mri #1
    iih adolescent #1
    case recurrent stroke #1
    neuropathy vision #1
    unusual headaches humans #1
    ischemic outcome assessment #1
    monitoring neurodegenerative disease #1
    monocular migraine #1
    intracranial process #1
    viable retina #1
    disc edema concern #1
    sudden hemorrhage infarction #1
    crao association #1
    signs common manifestations #1
    intraarterial injections crao #1
    iih biological monitoring #1
    ischemic optic ion #1
    acute crao efficacy #1
    patients iih #1
    formation intramural clot #1
    anemia intracranial pressure #1
    patients unusual headaches #1
    complémentaires nécessaires common #1
    visual loss apmppe #1
    sequential diagnostic search #1
    neuro ophthalmic symptoms #1
    urgent pathology #1
    ces accidents surviennent #1
    increasingly recognized stroke #1
    ophthalmologic conditions #1
    formal visual #1
    icp anemia #1
    necrosis bilateral #1
    tmvl patient #1
    intracranial hypertension iih #1
    retina exploratory work #1
    stroke neurology ophthalmology #1
    range 1093 months #1
    peuvent survenir jusqu #1
    large hemorrhagic infarctions #1
    cerebri retrospective #1
    visual deficits treatment #1
    factors hypercoagulability #1
    neuroophthalmic symptoms signs #1
    diagnostic strategy headaches #1
    stroke promising therapy #1
    tmvl patients age #1

    Key People For Intracranial Hypertension

    Top KOLs in the world
    John Douglas Pickard
    intracranial pressure head injury cerebral autoregulation
    Deborah Isa Friedman
    intracranial hypertension pseudotumor cerebri chronic migraine
    Michael Wall
    visual field pseudotumor cerebri intracranial hypertension
    Marek Czosnyka
    intracranial pressure cerebral autoregulation traumatic brain injury
    Anthony P Marmarou
    brain edema head injury intracranial pressure
    James J Corbett
    pseudotumor cerebri optic neuritis visual loss

    Valérie Biousse:Expert Impact

    Concepts for whichValérie Bioussehas direct influence:Intracranial hypertension,  Diagnostic error,  Optic neuropathy,  Homonymous hemianopia,  Visual loss,  Optic nerve,  Ocular fundus,  Fundus photography.

    Valérie Biousse:KOL impact

    Concepts related to the work of other authors for whichfor which Valérie Biousse has influence:Intracranial hypertension,  Optic nerve,  Multiple sclerosis,  Visual field,  Carotid artery,  Pseudotumor cerebri,  Magnetic resonance.



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    Departments of Ophthalmology and Neurology, Emory University School of Medicine, Atlanta, GA 404-778-5158, United States. Electronic address: vbiouss@emory.edu. | Department of Ophthalmology. | Department of Neurology. | Departments of Ophthalmology,