Masashi Suzuki: Influence Statistics

Masashi Suzuki

Masashi Suzuki

Faculty of Medicine, Department of Otorhinolaryngology, Head and Neck Surgery, Oita University, Oita, Japan | Department of Otolaryngology Head and Neck Surgery, Faculty of ...

Masashi Suzuki: Expert Impact

Concepts for which Masashi Suzuki has direct influence: Otitis media , Middle ear , Nasal vaccination , Intranasal immunization , Allergic rhinitis , Nontypeable haemophilus , Solitary fibrous tumor .

Masashi Suzuki: KOL impact

Concepts related to the work of other authors for which for which Masashi Suzuki has influence: Otitis media , Middle ear , Intranasal immunization , Spiral ligament , Haemophilus influenzae , Immune responses , Peritonsillar abscess .

KOL Resume for Masashi Suzuki

Year
2022

Faculty of Medicine, Department of Otorhinolaryngology, Head and Neck Surgery, Oita University, Oita, Japan

2021

Department of Otolaryngology & Head and Neck Surgery, Faculty of Medicine, Oita University, Oita, Japan

2019

1 Department of Otolaryngology, Faculty of Medicine, Oita University, Oita, Japan.

2018

Oita University, Faculty of Medicine, Department of Otolaryngology, Japan. Electronic address:

2017

Department of Otolaryngology, Head and Neck Surgery, Oita University Faculty of Medicine, Oita, Japan

2016

Department of Otolaryngology, Oita University Faculty of Medicine, 1-1 Idaigaoka, Hazama-machi, Yufu, Oita 879-5593, Japan

2015

Department of Otolaryngology, Faculty of Medicine, Oita University, Oita, Japan

2013

Department of Otolaryngology, Faculty of Medicine, Oita University, Oita 879-5593, Japan

2012

Department of Otolaryngology, Faculty of Medicine, Oita University, 1-1 Idaigaoka, Hazama-Machi, Yufu, Oita 879-5593, Japan

2011

Department of Otolaryngology, Oita University Faculty of Medicine, Yufu, Oita, Japan

2010

Department of Otolaryngology, Faculty of Medicine, Oita University, 1-1 Idaigaoka, Hazama-machi, Yufu, Oita 879-5593, Japan

2009

Department of Otolaryngology, Faculty of Medicine, Oita University, Oita,

Oita University Faculty of Medicine

2008

Otolaryngology, Faculty of Medicine, Oita University, Oita, Japan

2007

Department of Otolaryngology, Oita University Faculty of Medicine, 1-1 Idaigaoka, Hazama-machi, 879-5593, Oita, Yufu, Japan

2006

Otolaryngology, Faculty of Medicine, Oita University, Yufu and

From the Department of Otolaryngology (n.a., s.k., t.h., m.e., m.s.), Oita University Faculty of Medicine, 1-1 Idaigaoka, Hazama-machi, Yufu, Oita, Japan.

2005

Department of Otolaryngology, Faculty of Medicine, Oita University, 1-1 Idaigaoka, Hasama-machi, Oita 879-5593, Japan

2004

From the Departments of Otolaryngology, Faculty of Medicine, Oita University (k.m., t.h., i.i., m.s., g.m.), Oita, and Kagoshima University (y.k.), Kagoshima, Japan.

Department of Otolaryngology, Oita Medical University, 1-1 Idaigaoka, Hasama-machi, Oita 879-5593, Japan

2003

Department of Immunology and Allergy, Otorhinolaryngology, Oita Medical University, Oita, JAPAN

2002

Department of Otolaryngology, Oita Medical University Hospital, Oita Medical University, Japan

2001

Department of Otolaryngology, Oita Medical University, Hasama-machi, Oita 879-5593, Japan

2000

Department of Otolaryngology, Oita Medical University, 1-1 Idaigaoka, Hasama-cho, Oita 879-5593, Japan

1999

Department of Otolaryngology, Oita Medical University, 1-1, Idaigaoka, Hasama-machi, Oita 879-5593, Japan

1998

Department of Otolaryngology, Oita Medical University, Japan.

1997

Department of Otolaryngology Oita Medical University 1‐1 Idaigaoka, Hazama‐machi Oita‐gun, Oita‐ken 856‐55, Japan

1995

From the Division of Otolaryngology—Head and Neck Surgery, University of California, San Diego, and The Research Service, Veterans Administration, San Diego, California. Dr Suzuki is currently at the Department of Otolaryngology, Oita Medical University, Oita, Japan.

1992

Department of Otolaryngology, Medical College of Oita, Oita, Japan

1989

From the Department of Otolaryngology, Medical College of Oita, Oita, Japan.

1988

Department of Otolaryngology, Medical College of Oita, Japan.

Prominent publications by Masashi Suzuki

KOL-Index: 16777 . Nontypeable Haemophilus influenzae (NTHI) is a major pathogen of otitis media. One of the outer membrane proteins of NTHI, P6, is an antigen common to all strains and is considered as a candidate for mucosal vaccine. To elucidate the possibility of developing a nasal vaccine against nontypeable Haemophilus influenzae (NTHI) and to investigate mucosal immune responses in the middle ear, ...
Known for Intranasal Immunization | Middle Ear | Immune Responses | Nontypeable Haemophilus
KOL-Index: 12545 . OBJECTIVES: Nasal vaccination is an effective therapeutic regimen for preventing otitis media. Since cholera toxin (CT) is toxic, an alternative adjuvant is required for the development of a nasal vaccine. The efficacy of CpG oligodeoxynucleotide (ODN) as a mucosal adjuvant was examined. METHODS: Mice were immunized intranasally with P6 protein of non-typeable Haemophilus influenzae (NTHi) ...
Known for Nasal Vaccination | Cpg Oligodeoxynucleotide | Haemophilus Influenzae | Protective Immunity
KOL-Index: 12007 . Nontypeable Haemophilus influenzae (NTHi) is a major pathogen causing otitis media (OM). One of the outer membrane proteins of NTHi, P6, is a common antigen to all strains and is considered a candidate for mucosal vaccine. We have previously reported that intranasal immunization with P6 and cholera toxin (CT) could induce P6-specific immunoglobulin A (IgA) antibodies in the middle ear. In ...
Known for Intranasal Immunization | Otitis Media | Immunized Mice | Nontypeable Haemophilus
KOL-Index: 11523 . Nasal vaccination is an effective therapeutic regimen for preventing otitis media. In the development of nasal vaccine, an appropriate adjuvant is required. In the present study, we examined the efficacy of fms-like tyrosine kinase receptor-3 ligand (Flt3L) as a mucosal adjuvant. Flt3L was administered intranasally or peritoneally to mice, which were then immunized intranasally with P6 ...
Known for Haemophilus Influenzae | Nasal Vaccination | Immune Responses | Immunologic Administration
KOL-Index: 10602 . The Wnt signaling pathway is essential for normal development and organogenesis. However, inappropriate activation of Wnt signaling, which results in the nuclear translocation of β-catenin, is associated with the development of various types of neoplasm. In this study, we investigated possible mutations in the genes for components of this pathway, namely, CTNNB1 (the gene for β-catenin), ...
Known for Adenoid Cystic | Wnt Signaling | Components Pathway | Protein Carcinoma
KOL-Index: 10360 . Acute otitis media (AOM) is one of the most common infectious diseases in children. Nontypeable Haemophilus influenzae (NTHi) and Moraxella catarrhalis, Gram-negative bacteria, are considered major pathogens of AOM and respiratory tract infections. In this study, we used monophosphoryl lipid A (MPL) as a Toll-like receptor (TLR4) agonist to induce innate immune responses before challenge ...
Known for Moraxella Catarrhalis | Monophosphoryl Lipid | Mpl Nthi | Nasopharynx Mice
KOL-Index: 10050 . Nontypeable Haemophilus influenzae (NTHi) is associated with chronic otitis media (COM). In this study, we generated a murine model of COM by using eustachian tube (ET) obstruction and NTHi (10(7) CFU) inoculation into the tympanic bulla, and we investigated the relationship between regulatory T cells (Treg) and chronic inflammation in the middle ear. Middle ear effusions (MEEs) and middle ...
Known for Middle Ear | Nontypeable Haemophilus | Chronic Otitis Media | Mouse Model
KOL-Index: 10023 . Adenoid cystic carcinoma (ACC) is a common malignant neoplasm of the salivary gland. The mechanism underlying ACC carcinogenesis is not fully elucidated, although data on associated genetic alterations are accumulating. Cyclin-dependent kinase inhibitors (CKIs) act as tumor suppressors in various cancers, and aberrant methylation in the CKI gene promoter region has been linked to gene ...
Known for Salivary Gland | Kinase Inhibitor | Adenoid Cystic Carcinoma | Promoter Regions
KOL-Index: 9836 . To determine the efficacy of a mucosal vaccine against nontypeable Haemophilus influenzae (NTHi), mice were immunized nasally, orally, intratracheally, or intraperitoneally with NTHi antigen together with cholera toxin. Antigen-specific IgA antibody titers in nasal washes and the numbers of antigen-specific IgA-producing cells in nasal passages showed the greatest increases in mice ...
Known for Nasal Immunization | Haemophilus Influenzae | Mucosal Iga | Protective Immunity
KOL-Index: 9831 . To investigate the effect of proinflammatory cytokines on spiral ligament (SL) fibrocytes and regulation of cytokines by dexamethasone (Dex), in vitro studies were performed in murine secondary cell cultures. Cultured SL fibrocytes were stimulated with tumor necrosis factor-alpha (TNF-alpha), and the secretion of various mediators was measured by enzyme-linked immunosorbent assay (ELISA) ...
Known for Spiral Ligament | Necrosis Factor | Dexamethasone Dex | Cultured Fibrocytes
KOL-Index: 9295 . The efficacy of alpha-galactosylceramide (alpha-GalCer) as a mucosal adjuvant was examined. Mice were immunized intranasally with nontypeable Haemophilus influenzae (NTHi) P6 protein and alpha-GalCer. P6-specific antibody responses in the form of P6-specific IgA in nasal washes and serum IgG titers were significantly elevated. Splenic CD4(+) T cells expressed P6-specific Th1 and Th2 ...
Known for Nasal Vaccination | Haemophilus Influenzae | Outer Membrane | Immunologic Administration
KOL-Index: 8695 . This study was designed to investigate the expression of intercellular adhesion molecule-1 (ICAM-1) on the spiral modiolar vein (SMV) with its collecting venules (CVs) and the venules of the endolymphatic sac during inner ear inflammation. These data will further elucidate the role of adhesion molecules in extravasation of inflammatory cells from blood vessels during an inner ear immune ...
Known for Ear Inflammation | Intercellular Adhesion | Icam1 Expression | Endolymphatic Sac
KOL-Index: 8108 . Nontypeable Haemophilus influenzae (NTHi) is considered a major pathogen underlying middle ear infection. This study characterized the role of Toll-like receptor 4 in the innate immune responses to acute otitis media induced by NTHi in mice. We used C3H/HeJ mice, which have nonfunctional Toll-like receptor 4, and normal wild-type C3H/HeN mice. NTHi were injected into the tympanic bulla, ...
Known for Otitis Media | Innate Immune Responses | Middle Ear | Mouse Model
KOL-Index: 7845 . BACKGROUND: Survivin is highly expressed in cancer cells but shows little or no expression in normal tissues. Little is known about antibody responses to survivin in patients with head and neck cancer. METHODS: Anti-survivin antibody responses in patients with head and neck cancer were investigated by enzyme-linked immunosorbent assay. Anti-p53 antibody and squamous cell carcinoma antigen ...
Known for Neck Cancer | Antibody Responses | Survivin Patients | Clinical Significance

Key People For Otitis Media

Top KOLs in the world
#1
Charles D Bluestone
otitis media eustachian tube middle ear
#2
Jerome O Klein
otitis media middle ear newborn infant
#3
Jack L Paradise
otitis media tympanostomy tubes cleft palate
#4
Richard M Rosenfeld
otitis media clinical practice guideline cerumen impaction
#5
DAVID W TEELE
middle ear otitis media new zealand
#6
Bernard A Rosner
breast cancer blood pressure nurses health study

Faculty of Medicine, Department of Otorhinolaryngology, Head and Neck Surgery, Oita University, Oita, Japan | Department of Otolaryngology Head and Neck Surgery, Faculty of Medicine Oita University, 1-1 Idaigaoka, Yufu, Oita 8795593, Japan | Departme