• Disease
  • Heart
  • Heart Transplantation
  • B Bruno Reichart

    Prominent publications by B Bruno Reichart

    KOL Index score: 16674

    OBJECTIVES: Cyclosporine (INN: ciclosporin) A or tacrolimus have been used mostly in combination with azathioprine as primary immunosuppression after lung transplantation. Benefit or risk deriving from the combination with mycophenolate mofetil are yet unknown.

    METHODS: In a prospective, 2-center, open randomized trial, the combination of cyclosporine A, mycophenolate mofetil, and steroids was compared with tacrolimus, mycophenolate mofetil, and steroids as primary therapy after primary ...

    Also Ranks for: Mycophenolate Mofetil |  primary immunosuppression |  cyclosporine tacrolimus |  lung transplantation |  acute rejection
    KOL Index score: 15150

    BACKGROUND: In severe human heart failure, an increase in frequency of stimulation is accompanied by a reduced force of contraction in vivo and in vitro. The present study was aimed to investigate whether inotropic stimulation influences the inverse force-frequency relationship in failing human myocardium.

    METHODS AND RESULTS: The effects of the cAMP-independent positive inotropic agents ouabain (0.01 mumol/L) and BDF 9148 (0.1 mumol/L) as well as the beta-adrenoceptor agonist ...

    Also Ranks for: Frequency Relationship |  failing human |  inotropic stimulation |  force contraction |  nyha class
    KOL Index score: 13609

    Animal studies suggest that the endocannabinoid system (ECS) plays a role in the regulation of myocardial contractility and in the pathogenesis of heart failure. The current study aimed to proof the existence of endocannabinoid receptors on human ventricular myocardium and to determine whether human chronic heart failure (CHF) is associated with changes in endocannabinoid receptor expression and distribution. Expression of cannabinoid receptor 1 (CB1) and cannabinoid receptor (CB2) on ...

    Also Ranks for: Cannabinoid Receptor |  heart failure |  cb1 cb2 |  ecs role |  myocardial contractility
    KOL Index score: 13289

    OBJECTIVE: With the aim of performing a completely endoscopic coronary bypass anastomosis, we have undertaken an experimental and clinical study using robotic instrumentation and voice-controlled camera guidance.

    METHODS: The ZEUS Robotic Surgical System (Computer Motion Inc, Goleta, Calif) consists of three interactive robotic arms and a control unit, allowing the surgeon to move the instrument arms in a scaled down mode. The third arm (AESOP, Computer Motion) positions the endoscope ...

    Also Ranks for: Coronary Artery |  bypass graft |  assisted surgical |  lita lad |  computer motion
    KOL Index score: 13107

    OBJECTIVE: This study represents the development of a treatment and seeding procedure to improve endothelial cellular adhesion on glutaraldehyde-fixed valves.

    METHODS: Porcine aortic valves were fixed with 0.2% glutaraldehyde. Wall pieces of these valves had either no additional treatment (n = 4), incubation in M199 Earle (1x), with sodium carbonate at 2.2 g/L without l-glutamine for 24 hours (n = 4), or additional pretreatment with 5%, 10%, or 15% citric acid (three groups, n = 4 each). ...

    Also Ranks for: Aortic Valves |  autologous fibroblasts |  endothelial cells |  citric acid |  cell adhesion
    KOL Index score: 12651

    OBJECTIVE: To compare two thermodilution methods for the determination of cardiac output (CO)-thermodilution in the pulmonary artery (COpa) and thermodilution in the femoral artery (COa)-with each other and with CO determined by continuous pulse contour analysis (COpc) in terms of reproducibility, bias, and correlation among the different methods. Good agreement between the methods would indicate the potential of pulse contour analysis to monitor CO continuously and at reduced ...

    Also Ranks for: Arterial Thermodilution |  copc copa |  cardiac output |  contour analysis |  femoral artery
    KOL Index score: 12388

    Bronchiolitis obliterans syndrome (BOS) is the limiting factor to long-term survival after lung transplantation. Previous studies suggested respiratory viral tract infections are associated with the development of BOS. To identify the impact of virus detection in bronchoalveolar lavage (BAL) fluid, we analyzed BAL samples from 87 consecutive lung transplant recipients for human herpesvirus (HHV)-6, Epstein-Barr virus, Herpes simplex virus 1/2, Cytomegalovirus, respiratory syncytical ...

    Also Ranks for: Human Herpesvirus |  lung transplantation |  bronchiolitis obliterans |  acute rejection |  lavage fluid
    KOL Index score: 12278

    BACKGROUND: Tissue engineering of autologous heart valves with the potential to grow and to remodel represents a promising concept in pediatric cardiovascular surgery. Currently we are exploring the impact of cryopreserved human umbilical cord cells (CHUCCs) for the fabrication of tissue-engineered heart valves for patients diagnosed prenatally with congenital heart lesions, potentially enabling heart valve replacement in the early years of life.

    METHODS: Human umbilical cord cells were ...

    Also Ranks for: Tissue Engineering |  heart valves |  umbilical cord |  electron microscopy |  cryopreserved cells
    KOL Index score: 12251

    STUDY OBJECTIVES: A transpulmonary thermal-dye dilution (TDD) technique using cold indocyanine green dye was utilized to monitor cardiac index (CI) and preload in patients after heart transplantation. Preload, determined by intrathoracic blood volume index (ITBVI) and global end-diastolic volume index (GEDVI), was compared to central venous pressure (CVP) and pulmonary artery occlusion pressure (PAOP) and was correlated with stroke volume index (SVI).

    DESIGN: Prospective study.

    SETTING: ...

    Also Ranks for: Hemodynamic Monitoring |  paop itbvi |  svi gedvi |  dilution technique |  preload patients
    KOL Index score: 11962

    BACKGROUND: The astonishing thickness of the endothelial glycocalyx, which rivals that of endothelial cells in the microvasculature, was disclosed in the last 15 years. As already demonstrated, this structure plays a key role in the regulation of inflammation and vascular permeability.

    METHODS AND RESULTS: Two components of the glycocalyx, syndecan-1 and heparan sulfate, were measured in arterial blood of 18 patients undergoing surgery of the ascending aorta with cardiopulmonary bypass ...

    Also Ranks for: Endothelial Glycocalyx |  heparan sulfate |  cardiopulmonary bypass |  syndecan1 vascular |  adhesion molecule1
    KOL Index score: 11860

    STUDY OBJECTIVE: Arterial thermal dye dilution (TDDart) with the COLD system (Munich, Germany) allows measurement of cardiac index (CI), partial blood volumes, lung water, and liver function. The aim of the study was to determine agreement of TDDart measurements with pulmonary artery thermal dilution measurements (TDpa) and to assess the reproducibility of TDDart parameters.

    DESIGN: Prospective study.

    SETTING: ICU of a university hospital department of cardiac surgery.

    PATIENTS: Thirty ...

    Also Ranks for: Blood Volume |  liver function |  lung water |  indicator dilution |  measurement cardiac
    KOL Index score: 11721

    OBJECTIVE: Monitoring of cardiac preload is mainly performed by measurement of central venous and pulmonary capillary wedge pressure in combination with assessment of cardiac output, applying the pulmonary arterial thermal dilution technique. However, the filling pressures are negatively influenced by mechanical ventilation and the pulmonary artery catheter is criticized because of its inherent risks. Measurement of right atria, right ventricular, global end diastolic and intrathoracic ...

    Also Ranks for: Blood Volume |  central venous pressure |  cardiac surgery |  pulmonary artery catheter |  global diastolic
    KOL Index score: 11670

    OBJECTIVES: Health-related quality of life and patient satisfaction have become important end points in cardiac surgery. Post-traumatic stress disorder has been described in patients with life-threatening heart disease. In this study, we investigated the occurrence of post-traumatic stress disorder in a sample of patients after cardiac surgery and compared health-related quality of life and patient satisfaction between patients with and without evidence of post-traumatic stress ...

    Also Ranks for: Cardiac Surgery |  stress disorder |  post traumatic |  healthrelated quality |  patients life


    B Bruno Reichart: Influence Statistics

    Sample of concepts for which B Bruno Reichart is among the top experts in the world.
    Concept World rank
    mammary artery bypass #1
    10 years 74 #1
    svri parameters #1
    ecm sialb #1
    suppression cpb #1
    coronary doppler measurements #1
    svri baboons #1
    wound healing problems #1
    standardtherapy photopheresis #1
    valves citric #1
    endothelial activation pump #1
    ghrelin target #1
    xenograft baboon #1
    xenograft survival baboon #1
    p001 svi #1
    subgroup auc measurements #1
    cpb hbo2 #1
    myocardial areas patients #1
    tac patients rank #1
    mpaauc mpa concentrations #1
    mixed culture fibroblasts #1
    cardiac surgery pump #1
    homografts aortic position #1
    pca pcv #1
    wall pieces valves #1
    rossprocedure #1
    preformed antinongalantibodies #1
    vitro models pca #1
    conditioning higher expression #1
    valve prostheses survival #1
    heartstring #1
    atiii consumption combination #1
    modified inlay groups #1
    piglets baboon #1
    opcab 005 #1
    gvd simvastatin #1
    naivity #1
    hemoglobins humans hypoxia #1
    freedom acute rejection #1
    allograft mitral #1
    ppi liter #1
    liverperformance #1
    bioreactor new approach #1
    operation pulsecontour #1
    800 csammf #1
    cav iii #1
    mrna pstreg #1
    extrapulmonary tunnel #1
    proliferation ucmsc #1
    altered myocardial expression #1

    Key People For Heart Transplantation

    Top KOLs in the world
    Jon A Kobashigawa
    heart transplantation united states mycophenolate mofetil
    Leah Bennett Edwards
    lung transplantation international society united states
    James K Kirklin
    heart transplantation ventricular assist united states
    Donna M Mancini
    heart failure cardiac transplantation ventricular assist
    Josef Stehlik
    lung transplantation heart failure international society
    David C Naftel
    heart transplantation united states interagency registry

    B Bruno Reichart:Expert Impact

    Concepts for whichB Bruno Reicharthas direct influence:Heart transplantation,  Cardiac surgery,  Coronary artery,  Cardiopulmonary bypass,  Lung transplantation,  Cardiac transplantation,  Aortic valve,  Sympathetic reinnervation.

    B Bruno Reichart:KOL impact

    Concepts related to the work of other authors for whichfor which B Bruno Reichart has influence:Heart transplantation,  Cardiac surgery,  Cardiopulmonary bypass,  Coronary artery,  Endothelial glycocalyx,  Mycophenolate mofetil,  Myocardial infarction.



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    Transregional Collaborative Research Center 127, Walter Brendel Centre of Experimental Medicine, LMU Munich, Munich, Germany | Walter Brendel Center for Experimental Medicine, LMU Munich, Munich, Germany | Transregional Collaborative Research Center,