• Disease
  • Global
  • Global Burden
  • Simone Ferrero

    Prominent publications by Simone Ferrero

    KOL Index score: 16907

    BACKGROUND: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection.

    METHODS: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection ...

    Also Ranks for: Pulmonary Complications |  patients surgery |  30day mortality |  perioperative sars |  international cohort study
    KOL Index score: 11583

    Peri-operative SARS-CoV-2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS-CoV-2 infection. This international, multicentre, prospective cohort study included patients undergoing elective or emergency surgery during October 2020. Surgical patients with pre-operative SARS-CoV-2 infection were compared with those without previous SARS-CoV-2 infection. The primary outcome ...

    Also Ranks for: Surgery Patients |  sars‐cov‐2 infection |  child child |  international prospective |  operative sars
    KOL Index score: 9484

    OBJECTIVES: To evaluate the maternal and perinatal outcomes of pregnancies affected by SARS-CoV-2 infection.

    METHODS: This was a multinational retrospective cohort study including women with a singleton pregnancy and laboratory-confirmed SARS-CoV-2 infection, conducted in 72 centers in 22 different countries in Europe, the USA, South America, Asia and Australia, between 1 February 2020 and 30 April 2020. Confirmed SARS-CoV-2 infection was defined as a positive result on real-time ...

    Also Ranks for: Pregnant Women |  sars‐cov‐2 infection |  maternal mortality |  perinatal outcomes |  mechanical ventilation
    KOL Index score: 8812

    INTRODUCTION: Increased mortality has been demonstrated in older adults with coronavirus disease 2019 (COVID-19), but the effect of frailty has been unclear.

    METHODS: This multi-centre cohort study involved patients aged 18 years and older hospitalised with COVID-19, using routinely collected data. We used Cox regression analysis to assess the impact of age, frailty and delirium on the risk of inpatient mortality, adjusting for sex, illness severity, inflammation and co-morbidities. We ...

    Also Ranks for: Age Frailty |  covid19 risk |  adverse outcomes |  illness severity |  frail elderly
    KOL Index score: 8642

    BACKGROUND: In estimating the global burden of cancer, adolescents and young adults with cancer are often overlooked, despite being a distinct subgroup with unique epidemiology, clinical care needs, and societal impact. Comprehensive estimates of the global cancer burden in adolescents and young adults (aged 15-39 years) are lacking. To address this gap, we analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, with a focus on the outcome of ...

    Also Ranks for: Global Burden |  adult cancer |  study 2019 |  adolescent young |  years dalys
    KOL Index score: 8351

    Objectives To evaluate the strength of association between maternal and pregnancy characteristics and the risk of adverse perinatal outcomes in pregnancies with laboratory confirmed COVID-19. Methods Secondary analysis of a multinational, cohort study on all consecutive pregnant women with laboratory-confirmed COVID-19 from February 1, 2020 to April 30, 2020 from 73 centers from 22 different countries. A confirmed case of COVID-19 was defined as a positive result on real-time ...

    Also Ranks for: Neonatal Death |  secondary analysis |  trimester pregnancy |  gestational age |  risk vertical transmission
    KOL Index score: 6490

    OBJECTIVE: Sentinel node mapping (SLN) has replaced lymphadenectomy for staging surgery in apparent early-stage low and intermediate risk endometrial cancer (EC). Only limited data about the adoption of SNM in high risk EC is still available. Here, we evaluate the outcomes of high-risk EC undergoing SNM (with or without back-up lymphadenectomy).

    METHODS: This is a multi-institutional international retrospective study, evaluating data of high-risk (FIGO grade 3 endometrioid EC with ...

    Also Ranks for: Sentinel Node |  patients snm |  backup lymphadenectomy |  endometrial cancer |  nodal disease
    KOL Index score: 6289

    Biomass pretreatment aims at separating and providing easier access to the main biomass components (cellulose, hemicellulose and lignin), eventually removing lignin, preserving the hemicellulose, reducing the cellulose crystallinity and increasing the porosity of the material. Pretreatment is an essential step towards the development and industrialization of efficient 2nd generation lignocellulosic ethanol processes. The present work reviewed the main options available in pretreatment. ...

    Also Ranks for: Pretreatment Processes |  steam explosion |  lignocellulosic ethanol |  operating conditions |  new process
    KOL Index score: 5557

    Minimal residual disease (MRD) has been increasingly investigated in mantle cell lymphoma (MCL), including for individual therapeutic stratification and pre-emptive treatment in clinical trials. Although patient/allele specific real-time quantitative polymerase chain reaction (qPCR) of IGH or BCL1-IGH clonal markers is the gold-standard method, its reliance on a standard curve for relative quantification limits quantification of low-level positivity within the 1E-4 to 1E-5 range; over ...

    Also Ranks for: Mantle Cell Lymphoma |  droplet digital pcr |  quantitative range |  absolute quantification |  minimal residual disease
    KOL Index score: 5083

    SARS-CoV-2 has been associated with an increased rate of venous thromboembolism in critically ill patients. Since surgical patients are already at higher risk of venous thromboembolism than general populations, this study aimed to determine if patients with peri-operative or prior SARS-CoV-2 were at further increased risk of venous thromboembolism. We conducted a planned sub-study and analysis from an international, multicentre, prospective cohort study of elective and emergency patients ...

    Also Ranks for: Sars‐cov‐2 Infection |  venous thromboembolism |  surgery sars |  risk postoperative |  cohort patients
    KOL Index score: 5076

    We aimed to determine the impact of pre-operative isolation on postoperative pulmonary complications after elective surgery during the global SARS-CoV-2 pandemic. We performed an international prospective cohort study including patients undergoing elective surgery in October 2020. Isolation was defined as the period before surgery during which patients did not leave their house or receive visitors from outside their household. The primary outcome was postoperative pulmonary ...

    Also Ranks for: Elective Surgery |  pre‐operative isolation |  sarscov2 infection |  international prospective |  cov2 pandemic
    KOL Index score: 4765

    BACKGROUND: Fit patients with mantle cell lymphoma aged 18-65 years are usually given cytarabine and rituximab-based induction regimens followed by autologous haematopoetic stem-cell transplantation (HSCT). We investigated whether post-autologous HSCT maintenance with lenalidomide improves progression-free survival in this population.

    METHODS: This open-label, randomised, multicentre, phase 3 trial was done at 49 haematology and oncology units in Italy and Portugal. Eligible patients had ...

    Also Ranks for: Mantle Cell Lymphoma |  cell transplantation |  autologous haematopoietic |  fondazione italiana |  combined chemotherapy
    KOL Index score: 4214

    Patients with mantle cell lymphoma (MCL) that fail induction treatment represent a difficult-to-treat population, where no standard therapy exists. We evaluated outcomes in patients with first relapsed-refractory (r/r) MCL after upfront high dose cytarabine including standard regimens. Overall survival (OS-2) and progression-free survival (PFS-2) were estimated from the time of salvage therapy. The previously described threshold of 24 months was used to define patients as early- or ...

    Also Ranks for: Mantle Cell |  patients ibrutinib |  standard therapy |  lymphoma mcl |  24 months
    KOL Index score: 3892

    OBJECTIVE: To evaluate the outcomes of high-risk (HR) HPV-positive and -negative women affected by high-grade cervical dysplasia.

    METHODS: This is a retrospective multi-institutional study. Medical records of consecutive patients with high-grade cervical dysplasia undergoing conization between 2010 and 2014 were retrieved. All patients included had at least 5 years of follow-up. A propensity-score matching was adopted in order to reduce the presence of confounding factors between groups. ...

    Also Ranks for: Cervical Dysplasia |  primary conization |  multivariate analysis |  5 year |  risk recurrence
    KOL Index score: 3257

    BACKGROUND: The sustainable development goals (SDGs) aim to end HIV/AIDS as a public health threat by 2030. Understanding the current state of the HIV epidemic and its change over time is essential to this effort. This study assesses the current sex-specific HIV burden in 204 countries and territories and measures progress in the control of the epidemic.

    METHODS: To estimate age-specific and sex-specific trends in 48 of 204 countries, we extended the Estimation and Projection Package ...

    Also Ranks for: Hiv Incidence |  subsaharan africa |  global burden |  cases deaths |  people living


    Simone Ferrero: Influence Statistics

    Sample of concepts for which Simone Ferrero is among the top experts in the world.
    Concept World rank
    management distribution grids #1
    hormonal therapy endometriosis #3
    regional survey #5

    Key People For Global Burden

    Top KOLs in the world
    Christopher J L Murray
    global burden life expectancy united states
    Theo Vos
    global burden 195 countries life expectancy
    Jost Bruno Jonas
    axial length beijing eye study global burden
    Joshua A Salomon
    global burden united states south africa
    Farshad G Farzadfar
    global burden systematic analysis life expectancy
    Ted R Miller
    united states global burden 195 countries

    Simone Ferrero:Expert Impact

    Concepts for whichSimone Ferrerohas direct influence:Global burden,  Venous thromboembolism,  Patients surgery,  Mantle cell lymphoma,  Pulmonary complications,  Sars‐cov‐2 infection,  Elective surgery,  Network reconfiguration.

    Simone Ferrero:KOL impact

    Concepts related to the work of other authors for whichfor which Simone Ferrero has influence:Pregnant women,  Elective surgery,  Lignocellulosic biomass,  Enzymatic hydrolysis,  Surgical procedures,  Covid19 infection,  Bioethanol production.



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    Academic Unit of Obstetrics and Gynaecology, IRCCS Ospedale Policlinico San Martino, Genova, Italy | Division of Hematology, Department of Molecular Biotechnologies and Health Sciences, University of Torino, Turin, Italy. | Academic Unit of Obstetric