• Disease
  • Malignant
  • Malignant Melanoma
  • Christian Sigg

    Prominent publications by Christian Sigg

    KOL Index score: 5414

    To determine the prevalence of congenital melanoevocytic nevi (CMN), of so-called congenital nevus-like nevi (CNLN), nevi spili (NS) and café-au-lait spots (CLS) in childhood, a series of 939 children aged 8-16 years had total skin examination. CMN/CNLN were observed in a frequency of 5.9%, NS in 2.1% and CLS even in 32.7%. Except CLS (which occurred more frequently in boys), all of these lesions were equally represented in both sexes. According to the classification of Kopf and ...

    Also Ranks for: Congenital Nevi |  cmn cnln |  lait spots |  prevalence skin |  nevus pigmented
    KOL Index score: 4057

    In 939 schoolchildren aged 8-16 years skin complexion was determined by a system of seven categories Anamnestic data concerning tanning ability and history of sunburns, however, were not considered owing to their obvious unreliability in children. Mean nevus count was 17.97, was significantly higher in boys than in girls and increased with age. There was a clear relation of mean nevus number and skin complexion: in fair skin type nevi are most frequent, decreasing in number by increasing ...

    Also Ranks for: 939 Schoolchildren |  nevus count |  skin complexion |  hair color |  male melanoma
    KOL Index score: 3441

    To the Editor.— In 1947 Ota et al1 defined a rare combination of cutaneous hemangioma and pigmentary nevus as phacomatosis pigmentovascularis. The disorder was first subdivided into two types: type I, consisting of nevus flammeus and nevus pigmentosus et verrucosus, and type II, representing the association of nevus flammeus and aberrant mongolian spots. In 1966, Toda2 described the coexistence of nevus flammeus and nevus spilus as the third type. Finally, type IV was defined in 1979 by ...

    Also Ranks for: Nevus Spilus |  phacomatosis pigmentovascularis |  type iiib |  weber syndrome |  pigmented skin neoplasms
    KOL Index score: 2634

    Eight men with severe recessive x-linked ichthyosis were treated with acitretin, the main metabolite of etretinate, during four months. All of the patients showed marked clinical improvement of scaling during therapy. Hypervitaminosis A-type adverse reactions were observed in all patients. Although the overall tolerance was good, therapy was interrupted in one atopic patient because of pruritus. There were no undesirable laboratory changes in values. Thirty-five milligrams of acitretin ...

    Also Ranks for: Linked Ichthyosis |  severe recessive |  metabolite etretinate |  treated acitretin
    KOL Index score: 1806

    We prospectively analyzed skeletal changes of 16 patients who were treated with acitretin for various disorders of keratinization at doses of 10-50 mg/day (overall mean 0.4 mg/kg/day) for 7-12 months (mean 11.4 months). Skeletal changes from pretherapy findings were observed in 5 patients. In 4 of 5 patients they appeared to be linked to a preexisting degenerative pathology and could not be attributed to acitretin therapy. However, in 1 patient a spinal osseous side effect could not be ...

    Also Ranks for: Acitretin Therapy |  disorders keratinization |  spinal diseases |  retinoid induced
    KOL Index score: 1014
    Also Ranks for: Recessive Ichthyosis |  steryl sulfatase |  genetic linkage
    KOL Index score: 905

    In 2 cases with the classical clinical features described in connection with papillomatose papuleuse confluente et réticulée amyloid deposits could be demonstrated by histochemical (alkaline Congo red and thioflavin T reaction) and electron microscopical means. These results allow to discuss the nosological position of this disease.

    Also Ranks for: Skin Neoplasms |  male papilloma |  diagnosis differential |  réticulée gougerot
    KOL Index score: 479

    The successful immunotherapy by dinitrochlorobenzene in a 71-year-old woman suffering for 2 years from an exulcerated acrolentiginous melanoma is reported.

    Also Ranks for: Administration Topical |  skin neoplasms


    Christian Sigg: Influence Statistics

    Sample of concepts for which Christian Sigg is among the top experts in the world.
    Concept World rank
    giant nevus spilus #1
    etretinate months #2
    hypervitaminosis acitretin adult #2
    skin symptoms hypervitaminosis #2
    topical therapeutic modalities #2
    minimal effects beneficial #2
    chromosome acitretin #2
    agent symptomatic therapy #2
    acitretin daily efficacy #2
    acitretin symptomatic #2
    values thirtyfive milligrams #2
    therapy atopic patient #2
    agent interval therapy #2
    939 schoolchildren #2
    acitretin symptomatic therapy #2
    flammeus nevus #3
    thirtyfive milligrams #3
    acitretin agent #4
    pruritus values #4
    pruritus tretinoin #6
    cmn cnln children #6
    cmn cnln #6
    andrological investigations #8
    spilus nevus #10
    sporadic familial variants #16
    metabolite etretinate #21
    réticulée #24
    acitretin daily #24
    cnln #28
    acitretin metabolite #31
    nevus nevi #33
    carteaud #47
    abcde rule #49
    tretinoin chromosome #55
    ichthyosis severe #68
    skin complexion #68
    syndrome dns #70
    agent symptomatic #71
    gougerot carteaud #90
    xlinked recessive ichthyosis #91
    treated acitretin #95
    acitretin therapy #99

    Key People For Malignant Melanoma

    Top KOLs in the world
    Donald L Morton
    melanoma patients lymphatic mapping sentinel lymphadenectomy
    John Munn Kirkwood
    metastatic melanoma adjuvant therapy advisory consultancy
    Martin C Mihm
    malignant melanoma skin neoplasms clinical stage
    Arthur J Sober
    cutaneous melanoma clinical stage united states
    Charles M Balch†
    melanoma patients surgical oncology lymph node
    John F Thompson
    melanoma patients node biopsy sentinel lymph

    Christian Sigg:Expert Impact

    Concepts for whichChristian Sigghas direct influence:Malignant melanoma,  Dysplastic nevi,  Nevus spilus,  Dysplastic nevus,  Dysplastic nevus syndrome,  Symptomatic therapy,  Multiple primary melanomas,  Cmn cnln.

    Christian Sigg:KOL impact

    Concepts related to the work of other authors for whichfor which Christian Sigg has influence:Melanocytic nevi,  Reticulated papillomatosis,  Nevus spilus,  Sun exposure,  Urogenital tuberculosis,  Malignant melanoma,  Pigmented lesions.



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    Division of Andrology, Dermatology Clinic;, Division of Infectious Diseases and Hospital Epidemiology, Department of Medicine, and, Urology Clinic, University Hospital Zürich, Switzerland | Departments of, Dermatology and, Medical Radiology, Universi