Marburg Virus

[Joselyn-Ramos-MD]

This article has been medically reviewed by Joselyn Ramos, MD — 2022-2-6

Who are the top experts researching treatments for marburg virus?

The top experts researching marburg virus are: David Gura, Dr. Saskia Popescu and Jonathan Greenblatt.

What are some of the top places that specialize in marburg virus?

Recommended institutions that specialize in marburg virus:

Infections Managed, Inc. Stephen Renae A MD 1900 Randolph Rd Suite 216, Charlotte, NC 28207, United States3012 E Commercial Blvd, Fort Lauderdale, FL 33308, United States Phone: +19547769992

Med. Care Center City East practice 1012 Lucerne Ter, Orlando, FL 32806, United StatesGubener Str. 37, 10243 Berlin, Germany Phone: +493029363950

Infectious Disease Associates & Travel Medicine Clinic 6088 S Durango Dr #100, Las Vegas, NV 89113, United States Phone: +17022090388

Dr. med. Tobias Glaunsinger Danziger Str. 78b, 10405 Berlin, Germany Phone: +493044039972

Marburg Virus

[Joselyn-Ramos-MD]

This article has been medically reviewed by Joselyn Ramos, MD — 2022-2-6

#1	Heinz Feldmann
Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA | ... Ebola Virus | Hemorrhagic Fever | Nonhuman Primates | Monoclonal Antibodies | African Green Monkeys

#2	Thomas W Geisbert
Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA. | Galveston National Laboratory, Galveston, TX, 77550, USA; Department of ... Ebola Virus | Nonhuman Primates | Monoclonal Antibodies | Lassa Fever | Electron Microscopy

#3	Stuart T Nichol
Viral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease ... Ebola Virus | Hemorrhagic Fever | Rift Valley | United States | Sierra Leone

#4	Peter B Jahrling
Emerging Infectious Pathogens Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, MD 21702, USA | ... Ebola Virus | Guinea Pigs | Hemorrhagic Fever | Nonhuman Primates | Equine Encephalomyelitis

#5	Hans Dieter Klenk
Institute of Virology, Philipps University, Marburg, Germany | Institute of Virology, Philipps-University, Marburg, Germany | Institute for Virology, Philipps University of ... Influenza Virus | Cleavage Site | Insect Cells | Viral Glycoproteins | Cell Surface

#6	Pierre Etienne Rollin
1National Center for Emerging and Zoonotic Infectious Diseases, CDC; 2Department of Health Research Methods, Evidence, and Impact, McMaster University Hamilton, Ontario; ... Ebola Virus | United States | Hemorrhagic Fever | Democratic Republic | Monoclonal Antibodies

#7	Thomas G Ksiazek
Department of Pathology, University of Texas Medical Branch, Galveston, Tex. | Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA; ... Nipah Virus | United States | Hemorrhagic Fever | Democratic Republic | Rift Valley

#8	Jonathan S Towner
Centers for Disease Control and Prevention, Atlanta, GA | Centers for Disease Control and Prevention, Atlanta, GA USA | Viral Special Pathogens Branch, Division of ... Marburg Virus | Rousettus Aegyptiacus | Order Mononegavirales | Hemorrhagic Fever | Egyptian Rousette

#9	Stephan Becker
Institute of Virology, University of Marburg, 35043, Marburg, Germany | German Centre for Infection Research (DZIF), Partner site Giessen-Marburg-Langen, Marburg, Germany | ... Ebola Virus | Viral Transcription | Inclusion Bodies | Plasma Membrane | West Africa

#10	Viktor E Volchkov
Molecular Basis of Viral Pathogenicity, Centre International de Recherche en Infectiologie (CIRI), INSERMU1111-CNRS UMR5308, Université Claude Bernard Lyon 1, ENS de Lyon, ... Ebola Virus | Guinea Pigs | Gp Gene | Matrix Protein | Rna Editing

#11	Elke Mühlberger
National Emerging Infectious Diseases Laboratories, Boston University; Boston, Massachusetts, United States of America | Boston University | National Emerging Infectious ... Ebola Virus | Order Mononegavirales | Viral Inclusions | Pluripotent Stem Cells | Phylum Negarnaviricota

#12	Anthony Sanchez
Special Pathogens Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, . | Special Pathogens Branch, Div. of Viral ... Ebola Virus | Messenger Rna | Monoclonal Antibodies | Respiratory Tract | Hemorrhagic Fever

#13	Ute Ströher
Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America | Viral Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, ... Ebola Virus | United States | Sierra Leone | Hemorrhagic Fever | Lymphocytic Choriomeningitis

#14	Sherif R Zaki
From the Bacterial Special Pathogens Branch (J.E.G., W.A.B., J. Petras, M.G.E., L.L., D.D.B., C.A.G., Z.P.W., M.E.N., A.R.H.), the Poxvirus and Rabies Branch (A.K.), and the ... United States | West Nile | Zika Virus | Rocky Mountain | Disease Control

#15	Tara K Sealy
Centers for Disease Control and Prevention, Atlanta, GA USA | Viral Special Pathogens Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd. NE, 30329, Atlanta, ... Marburg Virus | Sierra Leone | Rousettus Aegyptiacus | Egyptian Rousette | Disease Control

#16	Lisa E Hensley
Integrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, MD 21702, USA. ... Ebola Virus | Nonhuman Primates | Middle East | Cynomolgus Macaques | Hemorrhagic Fever

#17	Sina Bavari
Division of Molecular Biology, United States Army Medical Research Institute of Infectious Diseases, Frederick, MD, United States | 21702, Helios, Frederick, MD, USA | ... Ebola Virus | Nonhuman Primates | Bacterial Superantigens | Botulinum Neurotoxin | Hemorrhagic Fever

#18	Kelly Lyn Warfield
Emergent BioSolutions, Gaithersburg, MD 20879, USA. | Emergent BioSolutions Inc, Gaithersburg, MD, USA | 61424Emergent BioSolutions Inc, Gaithersburg, MD, USA. | Emergent ... Ebola Virus | Nonhuman Primates | Antiviral Activity | Monoclonal Antibodies | Guinea Pigs

#19	Joan B Geisbert
Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA. | Department of Microbiology and Immunology, University of Texas Medical ... Ebola Virus | Nonhuman Primates | Monoclonal Antibodies | Lassa Fever | Guinea Pigs

#20	Yoshihiro Yoshihiro
Department of Virology, Institute of Medical Science, University of Tokyo, Tokyo, Japan | Center for Global Viral Diseases, National Center for Global Health and Medicine, ... Influenza Virus | Hong Kong | Amino Acid | Monoclonal Antibodies | Reverse Genetics

[Joselyn-Ramos-MD]

This article has been medically reviewed by Joselyn Ramos, MD — 2022-2-6

Transcriptional Profiling Of The Immune Response To Marburg Virus Infection

Marburg virus is a genetically simple RNA virus that causes a severe hemorrhagic fever in humans and nonhuman primates. The mechanism of pathogenesis of the infection is not well understood, ...

Marburg Virus | Immune Response | Infection Pathogenesis | Innate Leukocytes | Nonhuman Primates

Establishment And Characterization Of A Lethal Mouse Model For The Angola Strain...

.. with Marburg virus (MARV) and Ebola virus (EBOV) cause severe hemorrhagic fever in humans and nonhuman primates (NHPs) with fatality rates up to 90%. A number of experimental vaccine and ...

Marburg Virus | Mouse Model | Viral Sequence Analysis | Nonhuman Primates | Marv Angma

Development And Evaluation Of A Fluorogenic 5′-Nuclease Assay To Identify Marburg Virus

.. recognize Marburg virus infections is critical to quickly institute proper barrier nursing precautions and limit further spread of the disease. A rapid, sensitive, and specific laboratory ...

Marburg Virus | Future Outbreaks | Chain Reaction | Haemorrhagic Fever | Sensitivity Specificity

Sorting Of Marburg Virus Surface Protein And Virus Release Take Place At Opposite...

Marburg virus, a filovirus, causes severe hemorrhagic fever with hitherto poorly understood molecular pathogenesis. We have investigated here the vectorial transport of the surface protein GP ...

Marburg Virus | Surface Protein | Epithelial Cells | Apical Membrane | Culture Medium

Crystal Structure Of Marburg Virus Vp40 Reveals A Broad, Basic Patch For Matrix...

Marburg virus (MARV), a member of the filovirus family, causes severe hemorrhagic fever with up to 90% lethality. MARV matrix protein VP40 is essential for assembly and release of newly copied ...

Marburg Virus | Matrix Assembly | Marv Vp40 | Terminal Domain | Severe Hemorrhagic Fever

Marburg Virus Disease Outbreak In Kween District Uganda, 2017: Epidemiological...

.. for Marburg virus. Within 24 hour of confirmation, a rapid outbreak response was initiated. Here, we present results of epidemiological and laboratory investigations.

METHODS: A district ...

Marburg Virus | Blood Samples | Rapid Case | Disease Control | Outbreak Response

Variation In The Glycoprotein And Vp35 Genes Of Marburg Virus Strains

Marburg virus, the prototype of the family Filoviridae, differs genetically, serologically, and morphologically from Ebola viruses. To better define the genetic variation within the species, ...

Marburg Virus | Gp Gene | Amino Acid | Viral Sequence | Nonsynonymous Mutations

Basolateral Budding Of Marburg Virus: Vp40 Retargets Viral Glycoprotein Gp To The...

.. by Marburg virus (MARV). We found that MARV buds from the basolateral pole of hepatocytes and bile epithelial cells in infected guinea pigs, which leads to the release of infectious virus ...

Marburg Virus | Glycoprotein Gp | Basolateral Surface | Viral Proteins | Infectious Virions

The Vp40 Protein Of Marburg Virus Exhibits Impaired Budding And Increased...

.. The Marburg virus VP40 protein is a viral matrix protein that spontaneously buds from cells. It also functions as an interferon (IFN) signaling antagonist by targeting Janus kinase 1 ...

Marburg Virus | Mouse Adaptation | Matrix Protein | Ravv Vp40 | Ifn Antagonist

Shedding Of Marburg Virus In Naturally Infected Egyptian Rousette Bats, South Africa, 2017

.. detected Marburg virus RNA in rectal swab samples from Egyptian rousette bats in South Africa in 2017. This finding signifies that fecal contamination of natural bat habitats is a ...

Marburg Virus | Rousette Bats | South Africa | Animals Chiroptera | Natural Bat

How Severe And Prevalent Are Ebola And Marburg Viruses? A Systematic Review And...

.. and Marburg virus diseases are said to occur at a low prevalence, but are very severe diseases with high lethalities. The fatality rates reported in different outbreaks ranged from ...

Marburg Virus | Case Fatality | Ebola Humans | Published Literature | Hemorrhagic Fever

Comparison Of The Pathogenesis Of The Angola And Ravn Strains Of Marburg Virus In...

.. known Marburg virus (MARV) strains reveal 2 distinct genetic lineages: Ravn and the Lake Victoria Marburg complex (eg, Musoke, Popp, and Angola strains). Nucleotide variances of >20% ...

Marburg Virus | Guinea Pig | Marv Angola | Coagulation Parameters | Hemorrhagic Fever

A Recombinant Rabies Virus Expressing The Marburg Virus Glycoprotein Is Dependent...

Marburg virus (MARV) is a filovirus related to Ebola virus (EBOV) associated with human hemorrhagic disease. Outbreaks are sporadic and severe, with a reported case mortality rate of upward of ...

Marburg Virus | Neutralizing Antibodies | Vaccines Rabies | Cellular Cytotoxicity | Mice Inbred

Remdesivir (Gs-5734) Is Efficacious In Cynomolgus Macaques Infected With Marburg Virus.

Marburg virus (MARV) is a filovirus with documented human case-fatality rates of up to 90%. Here, we evaluated the therapeutic efficacy of remdesivir (GS-5734) in nonhuman primates ...

Marburg Virus | Therapeutic Efficacy | Nonhuman Primates | Remdesivir Gs5734 | Adenosine Monophosphate

Characterization Of Monoclonal Antibodies To Marburg Virus (Strain Musoke)...

.. with Marburg virus (strain Musoke) were evaluated for both biological activity and specificity. Several of the Marburg virus- (MBGV) specific MAbs reduced the size and/or number of MBGV ...

Marburg Virus | Monoclonal Antibodies | Protective Epitopes | Passive Transfer | Lethal Infection

Discovery And Early Development Of Avi-7537 And Avi-7288 For The Treatment Of...

.. and Marburg virus respectively. The discovery process involved identification of optimal transcript binding sites for PMO based RNA-therapeutics followed by screening for effective viral ...

Marburg Virus | Messenger Rna | Targeting Ebola | Approved Treatments | Chemical Modifications

Systematic Review Of Marburg Virus Vaccine Nonhuman Primate Studies And Human...

.. of Marburg virus underscore the need for an effective vaccine. A summary of the latest research is needed for this WHO priority pathogen. This systematic review aimed to determine progress ...

Marburg Virus | Nonhuman Primates | Challenge Studies | Viral Vaccines | Hemorrhagic Fever

Avi-7288 For Marburg Virus In Nonhuman Primates And Humans

.. encodes Marburg virus (MARV) nucleoprotein. Its safety in humans is undetermined.

METHODS: We assessed the efficacy of AVI-7288 in a series of studies involving a lethal challenge with ...

Marburg Virus | Nonhuman Primates | Phosphorodiamidate Morpholino | Antiviral Agents | Dose Study

Crystal Structure Of The Marburg Virus Vp35 Oligomerization Domain

Marburg virus (MARV) is a highly pathogenic filovirus that is classified in a genus distinct from that of Ebola virus (EBOV) (genera Marburgvirus and Ebolavirus, respectively). Both viruses ...

Marburg Virus | Crystal Structure | Oligomerization Domain | Immune Evasion | Marv Ebov

The Complete Nucleotide Sequence Of The Popp (1967) Strain Of Marburg Virus: A...

.. of Marburg virus strain Popp was determined. Strain Popp was isolated in 1967 during the first filoviral outbreak. The virus was purified from blood of infected guinea pigs in which it had ...

Marburg Virus | Amino Acid | Viral Proteins | Vero Cells | Coding Regions