Metastatic Bone Cancer

[Anny-Palencia-MD]

This article has been medically reviewed by Anny Palencia, MD — 2022-10-23

Who are the top experts researching treatments for metastatic bone cancer?

The top experts researching metastatic bone cancer are: R Catane, Teija O Sainio and Stephen Clarke.

What are the top concepts researched in studies about metastatic bone cancer?

The most researched concepts in studies of metastatic bone cancer are: Phase Iii, Solid Tumors, Evaluate Safety, Locally Advanced, Radiation Therapy and Tumor Cells.

What are some of the top places that specialize in metastatic bone cancer?

Recommended institutions that specialize in metastatic bone cancer:

Cromwell Hospital 164-178 Cromwell Rd, London SW5 0TU, United Kingdom Phone: +442074605700

Health Zoshin Clinic Japan, 〒102-0074 Tokyo, Chiyoda City, Kudanminami, 4 Chome−8−21, Yamawaki Bldg., ５F Phone: +81332371777

Orange Coast Oncology 300 Old Newport Blvd, Newport Beach, CA 92663 Phone: +19497220350

Bruckner Oncology 2330 Eastchester Rd, The Bronx, NY 10469 Phone: +17187324050

Metastatic Bone Cancer

[Anny-Palencia-MD]

This article has been medically reviewed by Anny Palencia, MD — 2022-10-23

#1	Christo A Angelov
Department of Chemistry, University of Alberta, Edmonton, Alberta T6G 2G2, Canada | Noujaim Institute, University of Alberta, Edmonton, Alberta, Canada. Metastatic Bone Cancer | Gemcitabine Bisphosphonate | Targeted Chemotherapy | Conjugate Bone | Female Kidney

#2	John R Mercer
University of Alberta Department of Oncology Edmonton Alberta Canada | Department of Oncology, University of Alberta, Cross Cancer Institute, 11560 University Avenue, Edmonton ... Tumor Hypoxia | Bone Metastases | Automated Synthesis | Nude Mice | Pyrimidine Nucleosides

#3	Amal A ElMabhouh
Millipore Sigma. | Department of Experimental Therapeutics, | Department of Oncology, Faculty of Medicine and Dentistry, Cross Cancer Institute, Edmonton, Alberta, Canada. | ... Bone Metastases | Gemcitabine Bisphosphonate | Fludarabine Bendamustine | Targeted Chemotherapy | Potential Bifunctional Agents

#4	Shun‐wu Fan
Key Laboratory of Musculoskeletal System Degeneration and Regeneration Translational Research of Zhejiang Province, Hangzhou, Zhejiang 310016, China. | Department of ... Intravertebral Cleft | Intervertebral Disc | Basivertebral Foramen | Multifidus Muscle | Cement Leakage

#5	Jianfeng Zhang
Department of Orthopaedic Surgery, Sir Run Run Shaw Hospital, Medical College of Zhejiang University, Hangzhou, China | Department of Orthopaedic Surgery, Sir Run Run Shaw ... Intervertebral Disc | Nucleus Pulposus | Osteoarthritis Treatment | Percutaneous Vertebroplasty | Balloon Kyphoplasty

#6	Michael Pazianas
Institute of Musculoskeletal Sciences, Oxford University, Oxford OX3 7LD, UK. Electronic address: michael.pazianas@ndorms.ox.ac.uk. | Institute of Musculoskeletal Sciences, ... Cytosolic Ca2 | Oral Bisphosphonate | Bone Resorption | Surrogate Marker | Colon Cancer

#7	Derek Hadar Rosenzweig
Division of Orthopaedic Surgery, McGill University, Montréal, QC, Canada | Injury, Repair and Recovery Program, Research Institute of McGill University Health Center, ... Tenogenic Differentiation | Mechanical Strain | Disc Cells | Chondrocyte Phenotype | Collagen Type

#8	Pouyan Ahangar
Department of Surgery, Division of Orthopaedic Surgery, McGill University, Canada | Department of Surgery, Division of Orthopaedic Surgery, McGill University | McGill ... Therapeutic Sensitivity | Musculoskeletal Repair | Bone Metastasis | Current Biomedical Applications | Additive Manufacturing

#9	Masaki Nogawa
Department of Transfusion Medicine and Cell Therapy, Graduate School of Medicine, Kyoto University, Kyoto, Japan | Department of Transfusion Medicine and Cell Therapy, Kyoto ... Bladder Cancer | Zoledronic Acid | Inbred Balb Mice | Surface Plasmon Resonance | Gammadeltat Cells

#10	Hidekazu Segawa
Department of Medicine, Shiga University of Medical Science, Setatsukinowa, Otsu, Shiga, Japan | Department of Transfusion Medicine and Cell Therapy, Kyoto University ... Imatinib Mesylate | Bladder Cancer | Zoledronic Acid | Malt Lymphoma | Calophyllum Brasiliense

#11	Elie Akoury
Department of Surgery, Division of Orthopaedics, McGill University and The Research Institute of the McGill University Health Centre, Injury Repair Recovery Program, Montreal, ... Nlrp7 Mutations | Live Births | Usher Syndrome | Bone Repair | Hydatidiform Mole

#12	Alfredo Salerno
University of Palermo Department of Biopathology and Biomedical Methodologies Palermo Italy | Department of Pathology and Biomedical Methodologies, University of Palermo, ... Contact Sensitivity | Mycobacterium Tuberculosis | Inbred Balb Mice | Newcastle Disease | Picryl Chloride

#13	Ana Sofia Ramirez Garcia Luna
National Institute of Respiratory Diseases, Neurology, Mexico City, Mexico | Facultad de Medicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí, Mexico | Facultad ... Mortality Prediction | Gold 2015 | Low Dose Zoledronate | Local Doxorubicin Delivery | Printed Scaffolds

#14	Nicola Margiotta
Dipartimento di Chimica, Università degli Studi di Bari “A. Moro”, Via Orabona 4, 70126, Bari, Italy | Dipartimento di Chimica, Università degli Studi di Bari Aldo Moro, Via ... Translocator Protein | Bone Tumors | Silica Xerogels | Axial Positions | Cytotoxic Activity

[Anny-Palencia-MD]

This article has been medically reviewed by Anny Palencia, MD — 2022-10-23

A 99mtc-Labeled Gemcitabine Bisphosphonate Drug Conjugate As A Probe To Assess...

INTRODUCTION: A novel compound with the potential for "targeted" therapy for cancer patients was prepared using a conjugate between the potent anticancer drug Gemzar (gemcitabine) and a ...

Metastatic Bone Cancer | Bisphosphonate Drug | Powdered Bovine Bone | Tissue Distribution | Inbred Balb

Preclinical Investigations Of Drug And Radionuclide Conjugates Of Bisphosphonates...

The potential targeting of therapeutic bisphosphonate conjugates to bone metastatic lesions was evaluated in vivo in mice. A bisphosphonate conjugate with 5-fluorouracil was synthesized as a ...

Metastatic Bone Cancer | Bisphosphonate Conjugate | Bone Neoplasms | Unbound Activity | Tissue Distribution

Radioisotopes For The Palliation Of Metastatic Bone Cancer: A Systematic Review

.. from metastatic bone cancer, whereas rhenium-186 and rhenium-188 are investigational. Radioisotopes are effective in providing pain relief with response rates of between 40% and 95%. Pain ...

Pain Relief | Metastatic Bone Cancer | Radioisotopes Bone | Chemotherapeutic Agents | Hot Spots

Anti-Tumor Effects Of Low Dose Zoledronate On Lung Cancer-Induced Spine Metastasis

Zoledronate (Zol) is an anti-resorptive/tumoral agent used for the treatment of many cancers including spinal bone metastasis. High systemic administration of a single dose is now the standard ...

Lung Cancer | Severe Effects | Bone Metastasis | Migration Invasion

High-Dose Samarium-153 Ethylene Diamine Tetramethylene Phosphonate: Low Toxicity...

.. treat metastatic bone cancer.

PATIENTS AND METHODS: Patients with locally recurrent or metastatic osteosarcoma or skeletal ...

Skeletal Irradiation | 153 Smedtmp | Bone Metastases | 30 Mci | Ethylene Diamine

Metal-Ion Speciation In Blood Plasma Incorporating The Tetraphosphonate,...

.. of metastatic bone cancer, this paper relates results obtained with 166Ho and 153Sm complexed to the bone seeking phosphonate, ...

Blood Plasma | Therapeutic Radiopharmaceuticals | Holmium Humans | Bone Cancer | Pain Palliation

Metal-Ion Speciation In Blood Plasma Incorporating The Bisphosphonate,...

.. for metastatic bone cancer, this paper relates results obtained with 166Ho complexed to the bone-seeking bisphosphonate, 1-hydroxy-4-aminopropililydenediphosphonate (APD). APD is itself a ...

Blood Plasma | Bone Cancer | Therapeutic Radiopharmaceuticals | Complex Formation Constants | Molecular Structure

A Thermodynamic Approach, Using Speciation Studies, Towards The Evaluation And...

.. for metastatic bone cancer, 117mSn with its conversion electrons of discrete energies shows low bone marrow toxicity, providing the opportunity to increase the administered dose. Selective ...

Blood Plasma | Pei Mp | Boneseeking Radiopharmaceuticals | Selective Uptake | Administered Dose

Radiation Treatment Decreases Bone Cancer Pain, Osteolysis And Tumor Size

.. and metastatic bone cancer in humans. However, the mechanism(s) responsible for pain relief after irradiation is unknown. To identify the mechanism through which radiation treatment ...

Cancer Pain | Radiation Treatment | Tumor Size | Decreases Bone | Inbred C3h

Morphine Treatment Accelerates Sarcoma‐induced Bone Pain, Bone Loss, And...

Metastatic bone cancer causes severe pain that is primarily treated with opioids. A model of bone cancer pain in which the progression of cancer pain and bone destruction is tightly controlled ...

Bone Cancer | Morphine Treatment | Murine Model | Spontaneous Fracture | Tumor Growth

Transcriptional Activation Of Collagenase‐3 By Transforming Growth Factor‐β1 Is...

.. in metastatic bone cancer, stimulates collagenase-3 expression in the human breast cancer cell line, MDA-MB231. Cycloheximide inhibited this stimulation, indicating that de novo protein ...

Transforming Growth | Transcriptional Activation | Cancer Cells | Matrix Metalloproteinase | Human Breast

Disease Modification Of Breast Cancer–induced Bone Remodeling By Cannabinoid 2...

.. malignancies, metastatic bone cancer causes bone destruction and severe pain. Although novel chemotherapeutic agents have increased life expectancy, patients are experiencing higher ...

Breast Cancer | Bone Remodeling | Receptor Agonists | Cannabinoid Cb2 | Cell Proliferation

153sm-Edtmp And 186re-Hedp As Bone Therapeutic Radiopharmaceuticals

.. for metastatic bone cancer. Biolocalization properties of these chelates in animals as well as the physical decay and production properties of the respective radionuclides are consistent ...

Therapeutic Radiopharmaceuticals | Animals Bone | Selective Uptake | Skeletal Lesions | 186re Hedp

Potential Of Targeted Drug Delivery System For The Treatment Of Bone Metastasis

.. and metastatic bone cancer, there is an urgent need to develop new drugs and drug delivery systems for safe and efficient clinical treatments. Hence this article describes the potential of ...

Bone Metastasis | Drug Delivery | Targeting Moieties | Animals Antineoplastic | Intensity Focused

A Cannabinoid 2 Receptor Agonist Attenuates Bone Cancer-Induced Pain And Bone Loss

.. catalepsy. Metastatic bone cancer causes severe pain in patients and is treated with analgesics such as opiates. Recent reports suggest that sustained opiates can produce paradoxical ...

Bone Cancer | Induced Pain | Receptor Agonist | Animal Models | Murine Model