• Disease
  • Juvenile
  • Juvenile Turbot
  • Jinghua Chen

    Prominent publications by Jinghua Chen

    KOL Index score: 11781

    A 12-week feeding trial was conducted to investigate the effects of dietary arginine (Arg), glutamine (Gln), and their interactions on growth performance, nonspecific immunity, disease resistance, and Arg catabolism in juvenile turbot (Scophthalmus maximus L.). The basal diet was formulated with white fish meal, soybean meal, and corn gluten meal to contain 50% crude protein and 12% crude lipid. Nine isoproteic and isolipidic experimental diets were formulated by supplementing the basal ...

    Also Ranks for: Juvenile Turbot |  dietary arg |  growth performance |  scophthalmus maximus |  glutamine gln
    KOL Index score: 9208

    This experiment investigated the effects of dissolved oxygen (DO) on the survival and immune responses of scallop Chlamys farreri. The scallops (initial mean dry weight of soft tissue 1.52+/-0.10 g) were cultivated in the seawater with different DO levels (8.5, 6.5, 4.5, and 2.5mg l(-1), respectively) for 21 d. Each treatment had triplicate groups of 35 animals. During the experimental period, the scallops were fed with Spirulina maxima, and water temperature ranged from 15.2 degrees C ...

    Also Ranks for: Immune Responses |  dissolved oxygen |  chlamys farreri |  sod activity |  water temperature
    KOL Index score: 8779

    A water-soluble glucan, namely, PD3, was isolated from the fruiting body of Dictyophora indusiata as the method reported previously. Its chemical structure was characterized by GC, FTIR, and (13)C NMR. The results indicated that PD3 is a (1-->3)-beta-D-glucan, with (1-->6)-beta-glucopyranoside side branches. The chain conformation and morphology of PD3 in aqueous solution were investigated by viscometry, rheometer, and laser light scattering (LLS) measurements, atomic force microscopy ...

    Also Ranks for: Chain Conformation |  dictyophora indusiata |  structural characterization |  fruiting body |  aqueous solution
    KOL Index score: 6185

    INTRODUCTION: The extent of optimal gastric resection for proximal gastric cancer (PGC) continues to remain controversial, and a final consensus is yet to be met. The current study aimed to compare the perioperative outcomes, postoperative complications, and overall survival (OS) of proximal gastrectomy (PG) versus total gastrectomy (TG) in the treatment of PGC through a meta-analysis.

    METHODS: We systematically searched PubMed, Embase, The Cochrane Library, and Web of Science for ...

    Also Ranks for: Proximal Gastrectomy |  gastric cancer |  postoperative complications |  pg tg |  perioperative outcomes
    KOL Index score: 5736

    Metablastin (also called p19, stathmin, prosolin, p18, Lap18, and oncoprotein 18) is a highly conserved, cytosolic 149-amino acid polypeptide that is expressed in immature vertebrate cells and undergoes extracellular factor- and cell cycle-regulated serine phosphorylation. The protein was shown recently to destabilize microtubules in vitro (Belmont, L., and Mitchison, T. J. (1996) Cell 84, 623-631). Here we demonstrate that microinjection of recombinant metablastin induces a loss of ...

    Also Ranks for: Destabilizing Activity |  antineoplastic agents |  microtubule proteins |  phosphorylation sites |  intact cells
    KOL Index score: 5522

    Our previous study has demonstrated that luteinized granulosa cells (GCs) have the potential to proliferate and that the telomerase activity (TA) of luteinized GCs may predict the clinical outcomes of IVF treatment. However, in the field of telomere research, there have always been different opinions regarding the significance of TA and telomere length (TL). Thus, in the present study, we compared the effects of these two parameters on IVF treatment outcomes in the same individuals. TL ...

    Also Ranks for: Telomerase Activity |  granulosa cells |  telomere length |  ivf treatment |  pregnancy outcomes
    KOL Index score: 4611

    BACKGROUND: To build a new and appropriate model of secondary intra-abdominal hypertension (IAH) in rats.

    METHODS: A total of 32 female Sprague-Dawley rats were randomized into four groups. Group I: the rats were hemorrhaged to a mean arterial pressure (MAP) of 40 mm Hg for 1 h and portal hypertension was induced by partial ligation of the portal vein 1 h later; Group II: after inducing portal hypertension, hemorrhagic shock of MAP of 40 mm Hg was induced and maintained for 1 h; Group ...

    Also Ranks for: Abdominal Hypertension |  secondary iah |  arterial pressure |  shock hemorrhagic |  sprague dawley
    KOL Index score: 4480

    The coronavirus disease 2019 (COVID-19) pandemic has led to worldwide efforts to understand the biological traits of the newly identified human coronavirus (HCoV-19) virus. In this mass spectrometry (MS)-based study, we reveal that out of 21 possible glycosites in the HCoV-19 spike protein (S protein), 20 are completely occupied by N-glycans, predominantly of the oligomannose type. All seven glycosylation sites in human angiotensin I converting enzyme 2 (hACE2) were found to be ...

    Also Ranks for: Spike Protein |  mass spectrometry |  human ace2 |  worldwide efforts |  posttranslational modifications
    KOL Index score: 4358

    Water-soluble and water-insoluble polysaccharide fractions were isolated from fruiting bodies of Ganoderma lucidum (rheishi) by extraction with phosphate buffer and 1 N sodium hydroxide solutions at different temperatures and investigated by high-performance liquid chromatography (HPLC), one- and two-dimensional 1H and 13C NMR, infrared (IR) spectroscopy, and other techniques. This work was prompted by Sone et al.’s earlier conclusion that similarly extracted, water-insoluble ...

    Also Ranks for: Ganoderma Lucidum |  chemical structure |  molecular weight |  infrared spectroscopy |  fruiting bodies
    KOL Index score: 4189

    The treatment of triple-negative breast cancer (TNBC) relies largely on chemotherapies. However, it is frequent that TNBC patients develop resistance to the chemotherapy drugs. Generation of drug-resistant cell lines facilitates the identification of drug resistance. Here, we established two paclitaxel (PTX)-resistant TNBC cancer cell lines using an intermittent and stepwise method and found that long non-coding RNA long intergenic non-protein-coding RNA p53-induced transcript ...

    Also Ranks for: Negative Breast |  coding rna |  cancer cells |  linc pint |  tnbc patients
    KOL Index score: 3944

    BackgroundAlzheimer’s disease has become a public health crisis globally due to its increasing incidence. The purpose of this study was to establish an early warning model using artificial neural network (ANN) for early diagnosis of AD and to explore early sensitive markers for AD.MethodsA population based nested case-control study design was used. 89 new AD cases with good compliance who were willing to provide urine and blood specimen were selected from the cohort of 2482 ...

    Also Ranks for: Artificial Neural Network |  alzheimer disease |  sensitivity specificity |  ann model |  applied develop
    KOL Index score: 2306

    A label-free electrochemical biosensor based on the triplex DNA-templated Ag/Pt bimetallic nanoclusters (triplex-Ag/PtNCs) and locked nucleic acid (LNA) modified X-shaped DNA probe was developed for the detection of single-nucleotide variant (SNV) related to β-thalassemia. Firstly, using triplex DNA as template, a site-specific and homogeneous Ag/PtNCs was prepared, which can effectively catalyze the 3,3,5,5-tetramethylbenzidine-H2O2 system and thus be employed as a signal reporter in ...

    Also Ranks for: Electrochemical Biosensor |  nucleic acid |  single nucleotide |  dna probes |  biosensing techniques
    KOL Index score: 2207

    RATIONALE AND OBJECTIVES: To investigate whether iodine quantification extracted from enhanced dual energy-computed tomography (DE-CT) is useful for distinguishing lung squamous cell carcinoma from adenocarcinoma and to evaluate whether a single scan evaluated during the venous phase (VP) can be substituted for scans evaluated during other phases.

    MATERIALS AND METHODS: Sixty-two patients with lung cancer (32 squamous cell carcinomas; 30 adenocarcinomas) underwent enhanced dual-phase ...

    Also Ranks for: Sensitivity Specificity |  venous phase |  computed tomography |  cell lung |  dual energy
    KOL Index score: 1819

    PurposeTo compare the neonatal birthweight of singletons derived from ICSI cycles with fresh or frozen–thawed epididymal sperm in patients with obstructive azoospermia.MethodsA total of 436 singletons derived from ICSI cycles with fresh (n = 220) or frozen–thawed (n = 216) epididymal sperm in obstructive azoospermia evaluated from 2012 to 2018 in the retrospective study. Multivariate generalized linear model was used to analyze the association between epididymal sperm cryopreservation ...

    Also Ranks for: Sperm Cryopreservation |  icsi frozen |  patients obstructive
    KOL Index score: 1772

    The corrosion inhibition behavior of mercaptobenzothiazole (MBT) on copper in 0.1 M H2SO4 solutions was investigated by bulk acoustic wave (BAW) sensor under open-circuit condition in this paper. The growth process of Cu-MBT complex film was monitored by the BAW sensor and the frequency shift curves were acquired. The frequency shift curves were fitted with a proposed model and the maximum frequency shift and the apparent rate constant of film formation were obtained. The relations ...

    Also Ranks for: Mercaptobenzothiazole Mbt |  corrosion inhibition


    Jinghua Chen: Influence Statistics

    Sample of concepts for which Jinghua Chen is among the top experts in the world.
    Concept World rank
    abdominal restraint #7
    mercaptobenzothiazole copper #11
    responses farreri #12
    farreri scallops #14
    body dictyophora #16
    secondary iah #19
    iah model #23
    025 licl #24
    metablastin #26
    lls viscometry #31
    length granulosa #34
    prosolin #38
    camouflaging glycans #38
    secondary intra #50
    farreri jones #51
    waterinsoluble polysaccharides #51
    1→3α glucan #63
    jones preston #69
    ivf treatment outcomes #69
    serine stathmin #77

    Key People For Juvenile Turbot

    Top KOLs in the world
    Kang‐Sen Mai
    growth performance large yellow croaker juvenile turbot
    Sadasivam J Kaushik
    rainbow trout sparus aurata oncorhynchus mykiss
    Wei Xu
    growth performance juvenile turbot large yellow croaker
    Qing‐Hui Ai
    large yellow croaker growth performance juvenile turbot
    Albert Kjartansson Imsland
    juvenile turbot gadus morhua atlantic salmon
    Sigurd Olav Stefansson
    atlantic salmon salmo salar juvenile turbot

    Jinghua Chen:Expert Impact

    Concepts for whichJinghua Chenhas direct influence:Juvenile turbot,  Dietary arg,  Growth performance,  Chain conformation,  Proximal gastrectomy,  Fruiting body,  Dictyophora indusiata,  Telomerase activity.

    Jinghua Chen:KOL impact

    Concepts related to the work of other authors for whichfor which Jinghua Chen has influence:Microtubule dynamics,  Dictyophora indusiata,  Stathmin expression,  Telomere length,  Proximal gastrectomy,  Telomerase activity,  Granulosa cells.



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    The School of Pharmacy, Fujian Medical University, 350108, Fuzhou, Fujian, People’s Republic of China | Key Laboratory of Gene Editing Screening and R&D of Digestive System Tumor Drugs, Chinese Academy of Medical Sciences and Peking Union Medical Col